The effects of female age on the outcome of testicular sperm extraction and intracytoplasmic sperm injection in infertile patients with azoospermia

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dc.contributor.authorAltay B.
dc.contributor.authorKefI A.
dc.contributor.authorTavmergen E.
dc.contributor.authorÇIkIlI N.
dc.contributor.authorSemerci B.
dc.contributor.authorGoker E.T.
dc.date.accessioned2019-10-27T00:24:25Z
dc.date.available2019-10-27T00:24:25Z
dc.date.issued2002
dc.departmentEge Üniversitesien_US
dc.description.abstractIntroduction: Testicular sperm extraction (TESE) is well-defined procedure for surgical sperm retrieval in obstructive and non-obstructive azoospermia. This study was focused on the effectiveness of testicular sperm extraction and intracytoplasmic sperm injection (ICSI) for azoospermic men with different female age subgroups. Materials and methods: A total of 107 men with azoospermia underwent TESE and ICSI treatment. The women were examined in three groups 20-29, 30-34 and 35 years or older. The main outcome in this study was fertilization and pregnancy rates with TESE and ICSI. Results: Spermatozoa were successfully retrieved during 97 of 107 (90.7%) TESE attempts, resulting in the fertilization of 286 of 563 (50.4%) injected metaphase II oocytes. Two hundred and fifty-five of them were transferred (89.8%). The clinical pregnancy rate and ongoing pregnancy rate per embryo transfer were 22.5% and 20.6% respectively. When comparing the fertilization and pregnancy rates, it was observed that women between the ages of 20-29 years had significantly higher pregnancy rates than women over 34 years of age (p < 0.05). Conclusion: The female age is a major factor in determining successful implantation in ICSI.en_US
dc.identifier.doi10.1023/A:1014425508427en_US
dc.identifier.endpage99en_US
dc.identifier.issn0301-1623
dc.identifier.issue1en_US
dc.identifier.pmid12090348en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage95en_US
dc.identifier.urihttps://doi.org/10.1023/A:1014425508427
dc.identifier.urihttps://hdl.handle.net/11454/23062
dc.identifier.volume33en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherAkademiai Kiado Rt.en_US
dc.relation.ispartofInternational Urology and Nephrologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectFemale ageen_US
dc.subjectFertilization rateen_US
dc.subjectIntracytoplasmic sperm injection (ICSI)en_US
dc.subjectTesticular sperm extraction (TESE)en_US
dc.titleThe effects of female age on the outcome of testicular sperm extraction and intracytoplasmic sperm injection in infertile patients with azoospermiaen_US
dc.typeArticleen_US

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