Apolipoprotein E gene polymorphism and polycystic ovary syndrome patients in Western Anatolia, Turkey

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dc.contributor.authorCetinkalp, Sevki
dc.contributor.authorKaradeniz, Muammer
dc.contributor.authorErdogan, Mehmet
dc.contributor.authorZengi, Ayhan
dc.contributor.authorCetintas, Vildan
dc.contributor.authorTetik, Asli
dc.contributor.authorEroglu, Zuhal
dc.contributor.authorKosova, Buket
dc.contributor.authorOzgen, A. Gokhan
dc.contributor.authorSaygili, Fusun
dc.contributor.authorYilmaz, Candeger
dc.date.accessioned2019-10-27T20:20:58Z
dc.date.available2019-10-27T20:20:58Z
dc.date.issued2009
dc.departmentEge Üniversitesien_US
dc.description.abstractDyslipidemia, cardiovascular disease and hypertension are more frequently seen in patients with PCOS than in normal patients. We aimed at evaluating the distribution of Apo E alleles that can influence cardiovascular risk of the PCOS patients and control subjects. In this study, 129 young women with PCOS and 91 healthy women were included. In all subjects we performed hormonal, biochemical and Apo E genetic analysis. The Apo E3 allele was found at a significantly higher frequency in the PCOS patient group compared with the control group. The Apo E2 allele was found at a significantly higher frequency in the control group compared with the patient group with PCOS. Although there were genotype and allele differences between control and patient groups in this study, no statistically significant change was determined in lipid and other cardiovascular risk factors in connection with allele and genotype.en_US
dc.identifier.doi10.1007/s10815-008-9280-8en_US
dc.identifier.endpage6en_US
dc.identifier.issn1058-0468
dc.identifier.issn1573-7330
dc.identifier.issue1en_US
dc.identifier.pmid19057990en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage1en_US
dc.identifier.urihttps://doi.org/10.1007/s10815-008-9280-8
dc.identifier.urihttps://hdl.handle.net/11454/41700
dc.identifier.volume26en_US
dc.identifier.wosWOS:000263834000001en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringer/Plenum Publishersen_US
dc.relation.ispartofJournal of Assisted Reproduction and Geneticsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectApolipoprotein E geneen_US
dc.subjectCardiovascular risk factorsen_US
dc.subjectHyperlipidemiaen_US
dc.subjectPolycystic ovary syndromeen_US
dc.titleApolipoprotein E gene polymorphism and polycystic ovary syndrome patients in Western Anatolia, Turkeyen_US
dc.typeArticleen_US

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