Long-term outcomes of mitral valve repair in children

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dc.authorid0000-0001-6495-1639
dc.authorid0000-0003-4129-2217
dc.authorid0000-0002-1679-8016
dc.authorid0000-0002-7878-7531
dc.authorid0000-0002-5717-0057
dc.contributor.authorTuncer, Osman Nuri
dc.contributor.authorErtugay, Serkan
dc.contributor.authorAkhundova, Mahsati
dc.contributor.authorLevent, Erturk
dc.contributor.authorAtay, Yuksel
dc.date.accessioned2025-04-29T12:29:02Z
dc.date.available2025-04-29T12:29:02Z
dc.date.issued2024
dc.departmentEge Üniversitesi, Tıp Fakültesi, Cerrahi Bilimler Bölümü, Kalp-Damar Cerrahisi Ana Bilim Dalı
dc.description.abstractBackground Mitral Valve Disease in children presents unique challenges due to the wide range of associated pathologies and the complexities of pediatric cardiac anatomy. Mitral valve repair in this demographic is preferred over replacement due to the drawbacks associated with prosthetic valves in young patients, such as the need for long-term anticoagulation and issues with prosthetic size and growth.Methods This retrospective study reviewed pediatric patients under 18 years who underwent mitral valve repair between January 2002 and December 2023. Exclusion criteria included patients with atrioventricular septal defects or single-ventricle physiology. Surgical outcomes were assessed using preoperative and postoperative transthoracic echocardiography, with follow-up data analyzed via Kaplan-Meier survival estimates.Results The study included 47 patients with a median age of 4 years. Surgical techniques varied based on the specific mitral valve pathology. The overall early mortality was 6.3%, and the one and ten-year survival rates were 93.6 +/- 3.6% and 91.4 +/- 4.1%, respectively. Most patients showed improved or stable postoperative cardiac function during a median follow-up of 105 months. Notably, the rate of freedom from re-operation at ten years was 85.1 +/- 6.9%, highlighting the durability of the surgical interventions.Conclusions Mitral valve repair in children demonstrates favorable long-term outcomes with low mortality and reoperation rates, particularly when performed at an older age to accommodate growth and avoid the complexities of smaller, more delicate cardiac structures. These findings suggest that mitral valve repair should be considered a viable and effective option for managing pediatric MVD, with a personalized approach essential for optimizing outcomes.
dc.identifier.citationTuncer, O. N., Ertugay, S., Akhundova, M., Levent, E., & Atay, Y. (2024). Long-term outcomes of mitral valve repair in children. Frontiers in Cardiovascular Medicine, 11.
dc.identifier.doi10.3389/fcvm.2024.1454649
dc.identifier.endpage7
dc.identifier.issn2297055X
dc.identifier.issueOct
dc.identifier.pmid39411173
dc.identifier.scopusqualityQ2
dc.identifier.startpage1
dc.identifier.urihttps://doi.org/10.3389/fcvm.2024.1454649
dc.identifier.urihttps://hdl.handle.net/11454/117182
dc.identifier.volume11
dc.identifier.wosWOS:001330980500001
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorTuncer, Osman Nuri
dc.institutionauthorErtugay, Serkan
dc.institutionauthorAkhundova, Mahsati
dc.institutionauthorAkhundova, Erturk
dc.institutionauthorAtay, Yuksel
dc.institutionauthorid0000-0001-6495-1639
dc.institutionauthorid0000-0003-4129-2217
dc.institutionauthorid0000-0002-1679-8016
dc.institutionauthorid0000-0002-7878-7531
dc.institutionauthorid0000-0002-5717-0057
dc.language.isoen
dc.publisherFrontiers Media SA
dc.relation.ispartofFrontiers in Cardiovascular Medicine
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectmitral valve annuloplasty
dc.subjectcardiac surgical procedures
dc.subjectmitral regurgitation
dc.subjectcongenital heart disease
dc.subjectmitral stenosis (MS)
dc.titleLong-term outcomes of mitral valve repair in children
dc.typeArticle

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