Biodistribution of Whey Protein Labeled with Tc-99m on Experimental Animals
| dc.contributor.author | Parlak, Yasemin | |
| dc.contributor.author | Tekin, Volkan | |
| dc.contributor.author | Müftüler, Fazilet Zümrüt Biber | |
| dc.contributor.author | Topal, Gökçen | |
| dc.contributor.author | Gümüşler, Gül | |
| dc.contributor.author | Akınlı, Mert | |
| dc.contributor.author | Avcıbaşı, Uğur | |
| dc.date.accessioned | 2023-01-12T20:27:30Z | |
| dc.date.available | 2023-01-12T20:27:30Z | |
| dc.date.issued | 2021 | |
| dc.department | N/A/Department | en_US |
| dc.description.abstract | In this study, whey protein was radiolabeled with $Tc-^{99m}$ using the SnCl2 reduction method. The paper electrophoresis technique was done in the radiochromatography studies. SF (saline solution) was used as a suitable mobile phase. At the same time, the labeling yield of ${}^{99m}Tc$WHEY was found to be about 95%. Then, lipophilicity and stability studies were carried out, respectively. Finally, imaging and biodistribution studies were completed using Albino Wistar Rats. In vivo studies showed that ${}^{99m}Tc$WHEY was accumulated in the breast, the ovaria and the pancreas. In conclusion, all results showed that ${}^{99m}Tc$WHEY may be helpful in the diagnosis of the breast, the ovaria and the pancreas in the future. | en_US |
| dc.identifier.doi | 10.15671/hjbc.656021 | |
| dc.identifier.endpage | 252 | en_US |
| dc.identifier.issn | 2687-475X | |
| dc.identifier.issue | 3 | en_US |
| dc.identifier.startpage | 243 | en_US |
| dc.identifier.trdizinid | 461866 | en_US |
| dc.identifier.uri | https://doi.org/10.15671/hjbc.656021 | |
| dc.identifier.uri | https://search.trdizin.gov.tr/yayin/detay/461866 | |
| dc.identifier.uri | https://hdl.handle.net/11454/80283 | |
| dc.identifier.volume | 49 | en_US |
| dc.indekslendigikaynak | TR-Dizin | en_US |
| dc.language.iso | en | en_US |
| dc.relation.ispartof | Hacettepe Journal of Biology and Chemistry | en_US |
| dc.relation.publicationcategory | Makale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
| dc.rights | info:eu-repo/semantics/openAccess | en_US |
| dc.title | Biodistribution of Whey Protein Labeled with Tc-99m on Experimental Animals | en_US |
| dc.type | Article | en_US |
