Global prevalence and genotype distribution of hepatitis C virus infection in 2015: a modelling study

Basit Öğe Kaydı
dc.contributor.authorBlach, Sarah
dc.contributor.authorZeuzem, Stefan
dc.contributor.authorManns, Michael
dc.contributor.authorAltraif, Ibrahim
dc.contributor.authorDuberg, Ann-Sofi
dc.contributor.authorMuljono, David H.
dc.contributor.authorWaked, Imam
dc.contributor.authorAlavian, Seyed M.
dc.contributor.authorLee, Mei-Hsuan
dc.contributor.authorNegro, Francesco
dc.contributor.authorAbaalkhail, Faisal
dc.contributor.authorAbdou, Ahmed
dc.contributor.authorAbdulla, Maheeba
dc.contributor.authorAbou Rached, Antoine
dc.contributor.authorAho, Inka
dc.contributor.authorAkarca, Ulus
dc.contributor.authorAl Ghazzawi, Imad
dc.contributor.authorAl Kaabi, Saad
dc.contributor.authorAl Lawati, Faryal
dc.contributor.authorAl Namaani, Khalid
dc.contributor.authorAl Serkal, Youssif
dc.contributor.authorAl-Busafi, Said A.
dc.contributor.authorAl-Dabal, Layla
dc.contributor.authorAleman, Soo
dc.contributor.authorAlghamdi, Abdullah S.
dc.contributor.authorAljumah, Abdulrahman A.
dc.contributor.authorAl-Romaihi, Hamad E.
dc.contributor.authorAndersson, Monique I.
dc.contributor.authorArendt, Vic
dc.contributor.authorArkkila, Perttu
dc.contributor.authorAssiri, Abdullah M.
dc.contributor.authorBaatarkhuu, Oidov
dc.contributor.authorBane, Abate
dc.contributor.authorBen-Ari, Ziv
dc.contributor.authorBergin, Colm
dc.contributor.authorBessone, Fernando
dc.contributor.authorBihl, Florian
dc.contributor.authorBizri, Abdul R.
dc.contributor.authorBlachier, Martin
dc.contributor.authorBlasco, Antonio J.
dc.contributor.authorMello, Carlos E. Brandao
dc.contributor.authorBruggmann, Philip
dc.contributor.authorBrunton, Cheryl R.
dc.contributor.authorCalinas, Filipe
dc.contributor.authorChan, Henry L. Y.
dc.contributor.authorChaudhry, Asad
dc.contributor.authorCheinquer, Hugo
dc.contributor.authorChen, Chien-Jen
dc.contributor.authorChien, Rong-Nan
dc.contributor.authorChoi, Moon Seok
dc.contributor.authorChristensen, Peer B.
dc.contributor.authorChuang, Wan-Long
dc.contributor.authorChulanov, Vladimir
dc.contributor.authorCisneros, Laura
dc.contributor.authorClausen, Mette R.
dc.contributor.authorCramp, Matthew E.
dc.contributor.authorCraxi, Antonio
dc.contributor.authorCroes, Esther A.
dc.contributor.authorDalgard, Olav
dc.contributor.authorDaruich, Jorge R.
dc.contributor.authorde Ledinghen, Victor
dc.contributor.authorDore, Gregory J.
dc.contributor.authorEl-Sayed, Manal H.
dc.contributor.authorErgor, Gul
dc.contributor.authorEsmat, Gamal
dc.contributor.authorEstes, Chris
dc.contributor.authorFalconer, Karolin
dc.contributor.authorFarag, Elmoubashar
dc.contributor.authorFerraz, Maria L. G.
dc.contributor.authorFerreira, Paulo R.
dc.contributor.authorFlisiak, Robert
dc.contributor.authorFrankova, Sona
dc.contributor.authorGamkrelidze, Ivane
dc.contributor.authorGane, Ed
dc.contributor.authorGarcia-Samaniego, Javier
dc.contributor.authorKhan, Amir Ghafoor
dc.contributor.authorGountas, Ilias
dc.contributor.authorGoldis, Adrian
dc.contributor.authorGottfredsson, Magnus
dc.contributor.authorGrebely, Jason
dc.contributor.authorGschwantler, Michael
dc.contributor.authorPessoa, Mario Guimaraes
dc.contributor.authorGunter, Jessie
dc.contributor.authorHajarizadeh, Behzad
dc.contributor.authorHajelssedig, Omer
dc.contributor.authorHamid, Saeed
dc.contributor.authorHamoudi, Waseem
dc.contributor.authorHatzakis, Angelos
dc.contributor.authorHimatt, Sayed M.
dc.contributor.authorHofer, Harald
dc.contributor.authorHrstic, Irena
dc.contributor.authorHui, Yee-Tak
dc.contributor.authorHunyady, Bela
dc.contributor.authorIdilman, Ramazan
dc.contributor.authorJafri, Wasim
dc.contributor.authorJahis, Rohani
dc.contributor.authorJanjua, Naveed Z.
dc.contributor.authorJarcuska, Peter
dc.contributor.authorJeruma, Agita
dc.contributor.authorJonasson, Jon G.
dc.contributor.authorKamel, Yasser
dc.contributor.authorKao, Jia-Horng
dc.contributor.authorKaymakoglu, Sabahattin
dc.contributor.authorKershenobich, David
dc.contributor.authorKhamis, Jawad
dc.contributor.authorKim, Young S.
dc.contributor.authorKondili, Loreta
dc.contributor.authorKoutoubi, Zaher
dc.contributor.authorKrajden, Mel
dc.contributor.authorKrarup, Henrik
dc.contributor.authorLai, Moon-sing
dc.contributor.authorLaleman, Wim
dc.contributor.authorLao, Wai-cheung
dc.contributor.authorLavanchy, Daniel
dc.contributor.authorLazaro, Pablo
dc.contributor.authorLeleu, Henri
dc.contributor.authorLesi, Olufunmilayo
dc.contributor.authorLesmana, Laurentius A.
dc.contributor.authorLi, Michael
dc.contributor.authorLiakina, Valentina
dc.contributor.authorLim, Young-Suk
dc.contributor.authorLuksic, Boris
dc.contributor.authorMahomed, Adam
dc.contributor.authorMaimets, Matti
dc.contributor.authorMakara, Mihaly
dc.contributor.authorMalu, Abraham O.
dc.contributor.authorMarinho, Rui T.
dc.contributor.authorMarotta, Paul
dc.contributor.authorMauss, Stefan
dc.contributor.authorMemon, Muhammad S.
dc.contributor.authorCorrea, Maria C. Mendes
dc.contributor.authorMendez-Sanchez, Nahum
dc.contributor.authorMerat, Shahin
dc.contributor.authorMetwally, Ammal M.
dc.contributor.authorMohamed, Rosmawati
dc.contributor.authorMoreno, Christophe
dc.contributor.authorMourad, Fadi H.
dc.contributor.authorMullhaupt, Beat
dc.contributor.authorMurphy, Kimberly
dc.contributor.authorNde, Helen
dc.contributor.authorNjouom, Richard
dc.contributor.authorNonkovic, Diana
dc.contributor.authorNorris, Suzanne
dc.contributor.authorObekpa, Solomon
dc.contributor.authorOguche, Stephen
dc.contributor.authorOlafsson, Sigurour
dc.contributor.authorOltman, Marian
dc.contributor.authorOmede, Ogu
dc.contributor.authorOmuemu, Casimir
dc.contributor.authorOpare-Sem, Ohene
dc.contributor.authorOvrehus, Anne L. H.
dc.contributor.authorOwusu-Ofori, Shirley
dc.contributor.authorOyunsuren, Tsendsuren S.
dc.contributor.authorPapatheodoridis, George
dc.contributor.authorPasini, Ken
dc.contributor.authorPeltekian, Kevork M.
dc.contributor.authorPhillips, Richard O.
dc.contributor.authorPimenov, Nikolay
dc.contributor.authorPoustchi, Hossein
dc.contributor.authorPrabdial-Sing, Nishi
dc.contributor.authorQureshi, Huma
dc.contributor.authorRamji, Alnoor
dc.contributor.authorRazavi-Shearer, Devin
dc.contributor.authorRazavi-Shearer, Kathryn
dc.contributor.authorRedae, Berhane
dc.contributor.authorReesink, Henk W.
dc.contributor.authorRidruejo, Ezequiel
dc.contributor.authorRobbins, Sarah
dc.contributor.authorRoberts, Lewis R.
dc.contributor.authorRoberts, Stuart K.
dc.contributor.authorRosenberg, William M.
dc.contributor.authorRoudot-Thoraval, Francoise
dc.contributor.authorRyder, Stephen D.
dc.contributor.authorSafadi, Rifaat
dc.contributor.authorSagalova, Olga
dc.contributor.authorSalupere, Riina
dc.contributor.authorSanai, Faisal M.
dc.contributor.authorAvila, Juan F. Sanchez
dc.contributor.authorSaraswat, Vivek
dc.contributor.authorSarmento-Castro, Rui
dc.contributor.authorSarrazin, Christoph
dc.contributor.authorSchmelzer, Jonathan D.
dc.contributor.authorSchreter, Ivan
dc.contributor.authorSeguin-Devaux, Carole
dc.contributor.authorShah, Samir R.
dc.contributor.authorSharara, Ala I.
dc.contributor.authorSharma, Manik
dc.contributor.authorShevaldin, Anatoly
dc.contributor.authorShiha, Gamal E.
dc.contributor.authorSievert, William
dc.contributor.authorSonderup, Mark
dc.contributor.authorSouliotis, Kyriakos
dc.contributor.authorSpeiciene, Danute
dc.contributor.authorSperl, Jan
dc.contributor.authorStarkel, Peter
dc.contributor.authorStauber, Rudolf E.
dc.contributor.authorStedman, Catherine
dc.contributor.authorStruck, Daniel
dc.contributor.authorSu, Tung-Hung
dc.contributor.authorSypsa, Vana
dc.contributor.authorTan, Soek-Siam
dc.contributor.authorTanaka, Junko
dc.contributor.authorThompson, Alexander J.
dc.contributor.authorTolmane, Ieva
dc.contributor.authorTomasiewicz, Krzysztof
dc.contributor.authorValantinas, Jonas
dc.contributor.authorVan Damme, Pierre
dc.contributor.authorvan der Meer, Adriaan J.
dc.contributor.authorvan Thiel, Ingo
dc.contributor.authorVan Vlierberghe, Hans
dc.contributor.authorVince, Adriana
dc.contributor.authorVogel, Wolfgang
dc.contributor.authorWedemeyer, Heiner
dc.contributor.authorWeis, Nina
dc.contributor.authorWong, Vincent W. S.
dc.contributor.authorYaghi, Cesar
dc.contributor.authorYosry, Ayman
dc.contributor.authorYuen, Man-fung
dc.contributor.authorYunihastuti, Evy
dc.contributor.authorYusuf, Aasim
dc.contributor.authorZuckerman, Eli
dc.contributor.authorRazavi, Homie
dc.date.accessioned2019-10-27T11:10:22Z
dc.date.available2019-10-27T11:10:22Z
dc.date.issued2017
dc.departmentEge Üniversitesien_US
dc.description.abstractBackground The 69th World Health Assembly approved the Global Health Sector Strategy to eliminate hepatitis C virus (HCV) infection by 2030, which can become a reality with the recent launch of direct acting antiviral therapies. Reliable disease burden estimates are required for national strategies. This analysis estimates the global prevalence of viraemic HCV at the end of 2015, an update of-and expansion on-the 2014 analysis, which reported 80 million (95% CI 64-103) viraemic infections in 2013. Methods We developed country-level disease burden models following a systematic review of HCV prevalence (number of studies, n=6754) and genotype (n=11 342) studies published after 2013. A Delphi process was used to gain country expert consensus and validate inputs. Published estimates alone were used for countries where expert panel meetings could not be scheduled. Global prevalence was estimated using regional averages for countries without data. Findings Models were built for 100 countries, 59 of which were approved by country experts, with the remaining 41 estimated using published data alone. The remaining countries had insufficient data to create a model. The global prevalence of viraemic HCV is estimated to be 1.0% (95% uncertainty interval 0.8-1.1) in 2015, corresponding to 71.1 million (62.5-79.4) viraemic infections. Genotypes 1 and 3 were the most common cause of infections (44% and 25%, respectively). Interpretation The global estimate of viraemic infections is lower than previous estimates, largely due to more recent (lower) prevalence estimates in Africa. Additionally, increased mortality due to liver-related causes and an ageing population may have contributed to a reduction in infections.en_US
dc.description.sponsorshipJohn C Martin Foundationen_US
dc.description.sponsorshipJohn C Martin Foundation.en_US
dc.identifier.doi10.1016/S2468-1253(16)30181-9en_US
dc.identifier.endpage176en_US
dc.identifier.issn2468-1253
dc.identifier.issue3en_US
dc.identifier.pmid28404132en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage161en_US
dc.identifier.urihttps://doi.org/10.1016/S2468-1253(16)30181-9
dc.identifier.urihttps://hdl.handle.net/11454/32387
dc.identifier.volume2en_US
dc.identifier.wosWOS:000426979400014en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElsevier Incen_US
dc.relation.ispartofLancet Gastroenterology & Hepatologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleGlobal prevalence and genotype distribution of hepatitis C virus infection in 2015: a modelling studyen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu