The carcinogenic effect of diethylnitrosamine in rats and the preventive role of chloramphenicol in such cases

Basit Öğe Kaydı
dc.contributor.authorGunel O.
dc.contributor.authorAksu Y.
dc.date.accessioned2019-10-27T08:00:15Z
dc.date.available2019-10-27T08:00:15Z
dc.date.issued1973
dc.departmentEge Üniversitesien_US
dc.description.abstractA total of 104 rats was divided into groups of 60, 30 and 14. The first group received 1.2 mg/kg diethylnitrosamine (DENA) orally for 18 mth; the second group, 1.5 mg/Kg DENA for 14 mth; and the third group, 1.5 mg/Kg DENA for 11 mth. Each group was divided into test and control subgroups. Chloramphenicol, added to make 2% of the ground food, was given to the rats in the control subgroups in addition to DENA. Routine autopsies were carried out on animals that died normally, and tumoral and nontumoral changes were examined. Most of the tumoral changes were in the liver following the administration of DENA. In a minor degree some changes were also encountered in bile ducts, lymphoid tissue, kidneys and the mucosal lining of the stomach. The preventive role of chloramphenicol against the carcinogenic effect was studied also.en_US
dc.identifier.endpage69en_US
dc.identifier.issn0304-4939
dc.identifier.issn0304-4939en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage53en_US
dc.identifier.urihttps://hdl.handle.net/11454/24663
dc.identifier.volume272en_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.relation.ispartofAegean Medical Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.titleThe carcinogenic effect of diethylnitrosamine in rats and the preventive role of chloramphenicol in such casesen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

Scopus İndeksli Yayınlar Koleksiyonu