Nitric oxide synthase and interferon-? receptor immunoreactivities in relation to ascending spinal pathways to thalamus, hypothalamus, and the periaqueductal grey in the rat

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dc.contributor.authorKayalioglu G.
dc.contributor.authorRobertson B.
dc.contributor.authorKristensson K.
dc.contributor.authorGrant G.
dc.date.accessioned2019-10-27T09:00:28Z
dc.date.available2019-10-27T09:00:28Z
dc.date.issued1999
dc.departmentEge Üniversitesien_US
dc.description.abstractThe retrograde tracer fluoro-gold was injected into the periaqueductal grey, thalamus or hypothalamus, and spinal cord sections were processed for neuronal nitric oxide synthase (nNOS) immunohistochemistry to investigate the relationships of nNOS immunoreactive, and spinomesencephalic, spinothalamic and spinohypothalamic projection neurones. In addition, in the lateral spinal nucleus the relationship between spinomesencephalic, -thalamic and -hypothalamic projection neurones, and nNOS and interferon-? receptor immunoreactive structures was investigated at the lumbar level. No single retrogradely labelled spinomesencephalic, -thalamic or -hypothalamic neurone showed nNOS immunoreactivity. In the lateral spinal nucleus, however, many fluoro-gold-labelled neurones were closely apposed by both nNOS and interferon-? receptor immunoreactive structures, especially prominent in the hypothalamic injection cases. This study gave no evidence for nNOS immunoreactivity in spinal neurones projecting to the periaqueductal grey, thalamus or hypothalamus, but suggests that in the lateral spinal nucleus such neurones are contacted by both nNOS- and interferon-? receptor-containing axon terminals.en_US
dc.identifier.doi10.1080/08990229970348en_US
dc.identifier.endpage290en_US
dc.identifier.issn0899-0220
dc.identifier.issue4en_US
dc.identifier.pmid10632025en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage280en_US
dc.identifier.urihttps://doi.org/10.1080/08990229970348
dc.identifier.urihttps://hdl.handle.net/11454/28067
dc.identifier.volume16en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherCarfax Publishing Companyen_US
dc.relation.ispartofSomatosensory and Motor Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectFluoro-golden_US
dc.subjectInterferon-? receptoren_US
dc.subjectLateral spinal nucleusen_US
dc.subjectNitric oxideen_US
dc.subjectNociceptionen_US
dc.subjectSpinal corden_US
dc.titleNitric oxide synthase and interferon-? receptor immunoreactivities in relation to ascending spinal pathways to thalamus, hypothalamus, and the periaqueductal grey in the raten_US
dc.typeArticleen_US

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