Retinal Angiomatous Proliferation: Multimodal Imaging Characteristics and Follow-up with Eye-Tracked Spectral Domain Optical Coherence Tomography of Precursor Lesions

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dc.contributor.authorÖztaş, Zafer
dc.contributor.authorMenteş, Jale
dc.date.accessioned2020-12-01T12:33:11Z
dc.date.available2020-12-01T12:33:11Z
dc.date.issued2018
dc.departmentEge Üniversitesien_US
dc.description.abstractObjectives: To present the multimodal imaging characteristics of precursor retinal angiomatous proliferation (RAP) lesions and follow-up results with eye-tracked spectral-domain optical coherence tomography (SD-OCT). Materials and Methods: Six eyes of 6 patients aged 77.5±5.9 years diagnosed with precursor RAP lesion were included in this prospective observational case series. Best corrected visual acuity (BCVA) measurement and complete ophthalmologic examination were performed for all subjects, as well as fundus photography (FP), fundus autofluorescence (FAF), SD-OCT, fluorescein angiography (FA), indocyanine green angiography (ICGA), optical coherence tomography angiography (OCTA), and their long-term follow-up results are presented. Results: the mean BCVA was 0.8±0.16 (0.6-1) Snellen and the mean follow-up was 26.3±14.8 months. Images of the precursor RAP lesions demonstrated no specific findings on FP and FAF, showed focal hypofluorescent foci with no leakage on FA and IGA, and appeared as extrafoveal small, round, well-defined, hyperreflective foci typically located in the outer retinal layers on SD-OCT B-scans with high sampling density. OCTA demonstrated the precursor lesions as the deep capillary plexus abnormalities in 3 eyes. Two eyes progressed to stage 1 RAP during the follow-up period. Conclusion: This study defined the diagnostic characteristics and clinical course of precursor RAP lesions. Our findings highlight the importance of B-scans with high sampling density for the diagnosis of precursor lesions and using eye-tracking mode SD-OCT during follow-up.en_US
dc.identifier.doi10.4274/tjo.03780
dc.identifier.endpage69en_US
dc.identifier.issn1300-0659
dc.identifier.issn2147-2661
dc.identifier.issue2en_US
dc.identifier.startpage66en_US
dc.identifier.urihttps://doi.org/10.4274/tjo.03780
dc.identifier.urihttps://app.trdizin.gov.tr//makale/TWpnNE1Ua3lNZz09
dc.identifier.urihttps://hdl.handle.net/11454/66485
dc.identifier.volume48en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.ispartofTürk Oftalmoloji Dergisien_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectGöz Hastalıklarıen_US
dc.titleRetinal Angiomatous Proliferation: Multimodal Imaging Characteristics and Follow-up with Eye-Tracked Spectral Domain Optical Coherence Tomography of Precursor Lesionsen_US
dc.typeArticleen_US

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