The role and efficacy of clozapine treatment in early-onset and very early-onset schizophrenia cases: discussion of five cases

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dc.contributor.authorPerçinel, İpek
dc.contributor.authorYazıcı, Kemal Utku
dc.contributor.authorErermiş, Hatice Serpil
dc.contributor.authorÖzbaran, Burcu
dc.contributor.authorKöse, Sezen Gökçen
dc.contributor.authorZemla, Joanna
dc.contributor.authorİdris, Bülent
dc.date.accessioned2020-12-01T12:25:58Z
dc.date.available2020-12-01T12:25:58Z
dc.date.issued2015
dc.departmentEge Üniversitesien_US
dc.description.abstractSchizophrenia is a serious mental disorder emerging at an early age, characterized by significant breakdowns in thought, perception and behavioral processes and withdrawal from human relationships. Psychopharmacologic and psychosocial approaches should be combined for the treatment of schizophrenia. Although the effects and side effects of both typical and atypical antipsychotics have been studied in adult patients in detail, studies in child and adolescent age groups are inadequate. Clozapine is a prototype of atypical antipsychotics and the first antipsychotic to be defined as atypical. Clozapine is often effective in cases in which typical and other atypical antipsychotics fail, and is accepted as the “gold standard” in the treatment of schizophrenia. in this paper, the effects and side effects of clozapine in five adolescent cases diagnosed with schizophrenia are discussed. Four of these cases showed that clozapine is effective in adolescent schizophrenia. While the four cases showing good responses to the treatment tolerated clozapine well, the other case (case 4) showed an apparent decreasing trend in neutrophil count a short while after starting the treatment and his medication was stopped at the request of his parents.en_US
dc.identifier.endpage73en_US
dc.identifier.issn1017-7833
dc.identifier.issn1302-9657
dc.identifier.issue1en_US
dc.identifier.startpage65en_US
dc.identifier.urihttps://app.trdizin.gov.tr//makale/TVRZNU5qY3pNdz09
dc.identifier.urihttps://hdl.handle.net/11454/65461
dc.identifier.volume25en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.ispartofKlinik Psikofarmakoloji Bültenien_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectFarmakoloji ve Eczacılıken_US
dc.titleThe role and efficacy of clozapine treatment in early-onset and very early-onset schizophrenia cases: discussion of five casesen_US
dc.typeArticleen_US

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