The serial changes of Perfusion Index in preterm infants with patent ductus arteriosus: Is perfusion index clinically significant?

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dc.contributor.authorTerek D.
dc.contributor.authorKoroglu O.A.
dc.contributor.authorUlger Z.
dc.contributor.authorYalaz M.
dc.contributor.authorKultursay N.
dc.date.accessioned2019-10-26T21:18:18Z
dc.date.available2019-10-26T21:18:18Z
dc.date.issued2016
dc.departmentEge Üniversitesien_US
dc.description.abstractBackground: Perfusion Index (PI) which reflects the peripheral blood flow may help early detection and treatment decision of hemodynamically significant patent ductus arteriosus (hsPDA) in preterm infants. The present study is designed to analyze the usefulness of PI level in early detection of hsPDA in preterm infants. METHODS: Preterm infants born before 36 gestational weeks were assessed for PI and simultaneous echocardiography. Based on echocardiography, each infant is categorized into no-PDA (group 1), non-hsPDA (group 2) and hsPDA (group 3). Heart rate (HR), mean arterial pressure (MAP), body temperature and oxygen saturation (SpO2) and concomitant PI were measured on days 1, 2, 3 and 4. RESULTS: In all preterm infants (N.=42) PI significantly increased from 0.7 on day 1 to 1.4 on day 4. The HR did not change by the days; however, the MAP increased on days 3 and 4 compared to day 1. In hsPDA group, the median PI was 0.7 (IQR, 0.4) on day 1 compared to 0.9 (IQR, 0.2) on day 2. PI is significantly lower in hsPDA group compared to no-PDA group on day 1 and 2; however, this difference disappeared at 48 hour on the intravenous ibuprofen treatment (on day 3 and 4). CONCLUSIONS: PI may predict the perfusion disorder and help to decide for treatment of hsPDA and was also helpful to monitor the response to treatment in hsPDA patients. © 2014 Edizioni Minerva Medica.en_US
dc.identifier.endpage255en_US
dc.identifier.issn0026-4946
dc.identifier.issue4en_US
dc.identifier.pmid27277201en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage250en_US
dc.identifier.urihttps://hdl.handle.net/11454/16496
dc.identifier.volume68en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherEdizioni Minerva Medicaen_US
dc.relation.ispartofMinerva Pediatricaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectDuctus arteriosusen_US
dc.subjectEchocardiographyen_US
dc.subjectInfanten_US
dc.subjectPatenten_US
dc.subjectPerfusionen_US
dc.subjectPrematureen_US
dc.titleThe serial changes of Perfusion Index in preterm infants with patent ductus arteriosus: Is perfusion index clinically significant?en_US
dc.typeArticleen_US

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