Deep sclerectomy with a nonabsorbable implant (T-Flux): preliminary results

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dc.contributor.authorAtes, H
dc.contributor.authorUretmen, O
dc.contributor.authorAndac, K
dc.contributor.authorAzarsiz, SS
dc.date.accessioned2019-10-27T18:59:06Z
dc.date.available2019-10-27T18:59:06Z
dc.date.issued2003
dc.departmentEge Üniversitesien_US
dc.description.abstractBackground: Deep sclerectomy is one of the two main types of nonpenetrating surgical methods of treating open-angle glaucoma. We aimed to determine, in a prospective study, the efficacy, success rate and complications of deep sclerectomy with implantation of a nonabsorbable drain made of highly hydrophilic acrylic (T-Flux). Methods: Twenty-five patients (25 eyes) with medically uncontrolled open-angle glaucoma were treated by deep sclerectomy with implantation of the T-Flux drain. We determined the rates of intraocular pressure (IOP) reduction, surgical success (four categories) and complications. To evaluate the efficacy of this new implant in detail, we compared the success rates with those in a group of patients matched for age, sex, diagnosis, preoperative IOP, number of preoperative antiglaucoma medications and previous ocular surgery who underwent successful viscocanalostomy. Results: For two eyes in the deep-sclerectomy group, surgery was converted to standard trabeculectomy owing to perforation of the trabeculo-Descemet's membrane during dissection of the corneal stroma. The following results apply to the remaining 23 eyes. After a mean follow-up period of 16.21 (standard deviation [SD] 3.93) months, the mean IOP had fallen from 26.26 (SD 4.3) mm Hg preoperatively to 17.60 (SD 4.35) mm Hg at the last postoperative visit (p = 0.000). The rate of complete success (IOP < 21 mm Hg without medication) was 86.9% at 1 month, 56.5% at 12 months and 39.1% at the last visit. The rates of qualified success (IOP < 21 mm Hg with or without medication) were 95.6%, 91.3% and 82.6%, respectively. No postoperative complications of the type that might occur after trabeculectomy were observed. Three eyes wit h an insufficient reduction in IOP underwent goniopuncture with a neodymium:YAG laser. Statistical analysis of the success rates revealed that deep sclerectomy with T-Flux implantation was comparable to viscocanalostomy at all postoperative visits (p > 0.05). Interpretation: A statistically significant drop of IOP with few postoperative complications over the short term was achieved with deep sclerectomy and T-Flux implantation. The success rates were comparable to, and not significantly better than, those of viscocanalostomy.en_US
dc.identifier.doi10.1016/S0008-4182(03)80027-3en_US
dc.identifier.endpage488en_US
dc.identifier.issn0008-4182
dc.identifier.issn1715-3360
dc.identifier.issue6en_US
dc.identifier.pmid14620036en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage482en_US
dc.identifier.urihttps://doi.org/10.1016/S0008-4182(03)80027-3
dc.identifier.urihttps://hdl.handle.net/11454/37586
dc.identifier.volume38en_US
dc.identifier.wosWOS:000186001700006en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherCanadian Ophthal Socen_US
dc.relation.ispartofCanadian Journal of Ophthalmology-Journal Canadien D Ophtalmologieen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectglaucomaen_US
dc.subjectsclerectomyen_US
dc.subjectviscocanalostomyen_US
dc.subjectglaucoma drainage implantsen_US
dc.subjectintraocular pressureen_US
dc.titleDeep sclerectomy with a nonabsorbable implant (T-Flux): preliminary resultsen_US
dc.typeArticleen_US

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