Clinical efficacy of the smartplug (TM) in the treatment of primary Sjogren's syndrome with keratoconjunctivitis SICCA: one-year follow-up study

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dc.contributor.authorEgrilmez, Sait
dc.contributor.authorAslan, Fatih
dc.contributor.authorKarabulut, Gonca
dc.contributor.authorKabasakal, Yasemin
dc.contributor.authorYagci, Ayse
dc.date.accessioned2019-10-27T21:35:18Z
dc.date.available2019-10-27T21:35:18Z
dc.date.issued2011
dc.departmentEge Üniversitesien_US
dc.description.abstractTo evaluate the efficacy of a thermo-sensitive punctum plug, (SmartPlug (TM)) in Primary Sjogren's Syndrome (pSS) patients with dry eyes, whose symptoms persist despite preservative-free artificial tear treatment. In this study, 22 Primary Sjogren's Syndrome (pSS), as defined by American-European Consensus Group Classification Criteria. All patients being followed up by Ege University Departments of Rheumatology and Ophthalmology. The patients had positive Schirmer test results (< 5 mm without anesthesia). SmartPlug (TM) (Medennium, Irvine, California, USA) was inserted into the inferior lacrimal canaliculi of both eyes. Visual acuity measurements, Schirmer I test measurements, lissamine green staining scores, and tear-film breakup times (BUT) were noted before plug insertion and at the 1st, 6th, and 12th months following the procedure. Minimum follow-up period was 6 months for 19 patients and 12 months for 16 patients. Significant improvements were seen in the Schirmer I test scores (before insertion: 1.98 +/- A 2.67; 1st month: 5.68 +/- A 6.69; 6th month: 5.35 +/- A 5.38; 12th month 6.43 +/- A 5.14 P = 0.006), tear-film BUT in seconds (before insertion: 4.64 +/- A 3.7; 1st month: 5.80 +/- A 2.36; 6th month: 7.53 +/- A 2.92; 12th month 7.50 +/- A 2.52, P < 0.0001), respectively. Thermodynamic punctum plug insertion only in inferior canaliculus is a simple, effective, and comfortable option for treatment of severe aqueous tear deficiency that cannot be controlled using preservative-free tears.en_US
dc.identifier.doi10.1007/s00296-010-1527-xen_US
dc.identifier.endpage1570en_US
dc.identifier.issn0172-8172
dc.identifier.issue12en_US
dc.identifier.pmid20490802en_US
dc.identifier.startpage1567en_US
dc.identifier.urihttps://doi.org/10.1007/s00296-010-1527-x
dc.identifier.urihttps://hdl.handle.net/11454/45828
dc.identifier.volume31en_US
dc.identifier.wosWOS:000297345900006en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringer Heidelbergen_US
dc.relation.ispartofRheumatology Internationalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectDry eyeen_US
dc.subjectSjogren syndromeen_US
dc.subjectPunctal plugen_US
dc.subjectSmartplugen_US
dc.subjectKeratoconjunctivitis siccaen_US
dc.titleClinical efficacy of the smartplug (TM) in the treatment of primary Sjogren's syndrome with keratoconjunctivitis SICCA: one-year follow-up studyen_US
dc.typeArticleen_US

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