Lead exposure and urinary N-acetyl ß D glucosaminidase activity in adolescent workers in auto repair workshops
Küçük Resim Yok
Tarih
2002
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Purpose: To investigate levels of lead (Pb) exposure and renal tubular damage among adolescent workers in auto repair workshops in Turkey. Methods: The study was conducted on 39 adolescent workers (mean age: 16.18±3.19 years) in auto repair workshops (8 autoelectrician, 10 motor repairman, 8 auto painter, 5 turner, 8 bonnet straighter). Thirteen adult employees of battery production in the workshops (mean age: 32.08±10.94 years) and 29 healthy rural adolescent (mean age: 14.78±2.68 years) constituted the control groups. The level of blood Pb was investigated by an atomic absorption spectrophotometer and urinary N-acetyl ß- D glucosaminidase (NAG) activity was measured by a colorimetric method. Mann-Whitney U test was performed to examine group differences. Results: All subjects and controls had normal blood urea, creatinine, uric acid, sodium, potassium levels, normal routine urine examination and tubular phosphorus reabsorption. Blood Pb levels in auto repair workers (8.13±7.41µg/dL) were significantly higher than the rural control group (3.49±1.39µg/dL) but lower than the battery workers (25.27±9.82µg/dL). Urinary NAG (U/gr creatinine) (4.71±2.11) was lower than the battery workers (7.39±4.37), however significantly higher than the normal control group (3.07±1.20). In addition, auto painters had higher levels of Pb exposure and urinary NAG activity than the other workers (p < .05). Conclusion: Chronic low dose Pb exposure was found to cause renal tubular injury in children workers of auto repair workshops. © Society for Adolescent Medicine, 2002.
Açıklama
Anahtar Kelimeler
Adolescents, Auto repair workers, Lead exposure, Nephrotoxicity, Turkey, Urinary N-acetyl -ß D glucosaminidase
Kaynak
Journal of Adolescent Health
WoS Q Değeri
Scopus Q Değeri
Q1
Cilt
30
Sayı
3
