The outcome of peripartum cardiomyopathy patients-single center experience

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dc.authoridYilmaz, Elfin Burcu/0000-0002-8584-5832
dc.authoridYeniyol, Sevket/0000-0002-2775-4406
dc.authoridBayazit Candemir, Yesim/0000-0001-5926-8499
dc.authoridCINKOOGLU, AKIN/0000-0003-3396-3949
dc.authoridCandemir, Aytac/0000-0002-5872-180X
dc.authorscopusid40261271800
dc.authorscopusid35069008100
dc.authorscopusid23993736300
dc.authorscopusid57204620887
dc.authorscopusid57218935285
dc.authorscopusid57890011300
dc.authorscopusid57989874500
dc.contributor.authorDemir, Emre
dc.contributor.authorCeylan, Naim
dc.contributor.authorBayraktaroglu, Selen
dc.contributor.authorCinkooglu, Akin
dc.contributor.authorCandemir, Aytac
dc.contributor.authorCandemir, Yesim B.
dc.contributor.authorGunes, Mustafa Talha
dc.date.accessioned2023-01-12T20:01:50Z
dc.date.available2023-01-12T20:01:50Z
dc.date.issued2022
dc.departmentN/A/Departmenten_US
dc.description.abstractObjectivePeripartum cardiomyopathy (PPCM) diagnosis made by excluding identifiable causes of heart failure (HF) and occurs end of the pregnancy or during the postpartum period of five months. It presents a clinical HF spectrum with left ventricular systolic dysfunction. BackgroundThe purpose of this study is to retrospectively evaluate the clinical characteristics, cardiac magnetic resonance (CMR) imaging features, and end-points consisting of left ventricle recovery, left ventricular assist device implantation, heart transplantation, and all-cause mortality. MethodOutpatient HF records between 2008 to 2021 were screened. Thirty-seven patients were defined as PPCM. Twenty-five patients had CMR evaluation at the time of diagnosis, and six patients were re-evaluated with CMR. ResultsThe mean age was 30.5 +/- 5.6 years, and the mean LVEF was 28.2% +/- 6.7%. In 13(35.7%) patients, LVEF recovered during the follow-up course. The median recovery time was 281(IQR [78-358]) days. LVEF on CMR was 35.3 +/- 10.5, and three patients exhibited late gadolinium enhancement(LGE) patterns. Sub-endocardial and mid-wall uptake pattern types were detected. 18(75%) patients met the Petersen left ventricle non-compaction cardiomyopathy(LVNC) criteria. Patients with NC/C ratio lower than 2.3 had lower LVEDVi and LVESVi (124.9 +/- 35.4, 86.4 +/- 7.5, p = .003; 86.8 +/- 34.6, 52.6 +/- 7.6, p = .006), respectively. The median follow-up time was 2129 (IQR [911-2634]) days. The primary endpoint-free 1-year survival was 88.9% (event rate 11.1%), and 5-year survival was 75.7% (event rate 24.3%). ConclusionIn a retrospective cohort of PPCM patients, 35.7% of patients' LVEF recovered, and the primary end-point of free-5-year survival was 75%. Twenty-five patients were assessed with CMR; three of four met the Petersen CMR-derived LVNC at initial evaluation.en_US
dc.identifier.doi10.1111/echo.15498
dc.identifier.endpage1615en_US
dc.identifier.issn0742-2822
dc.identifier.issn1540-8175
dc.identifier.issue12en_US
dc.identifier.pmid36447302en_US
dc.identifier.scopus2-s2.0-85143148384en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage1608en_US
dc.identifier.urihttps://doi.org/10.1111/echo.15498
dc.identifier.urihttps://hdl.handle.net/11454/77522
dc.identifier.volume39en_US
dc.identifier.wosWOS:000891996500001en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofEchocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniquesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectcardiac magnetic resonance imagingen_US
dc.subjectnon-compaction cardiomyopathyen_US
dc.subjectperipartum cardiomyopathyen_US
dc.subjectLeft-Ventricular Noncompactionen_US
dc.subjectManagementen_US
dc.subjectDiagnosisen_US
dc.subjectFeaturesen_US
dc.subjectWomenen_US
dc.subjectStateen_US
dc.titleThe outcome of peripartum cardiomyopathy patients-single center experienceen_US
dc.typeArticleen_US

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