Acute Lithium Neurotoxicity: Clinical and Electrophysiological Evaluation of Four Cases

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dc.contributor.authorKeles, Esra
dc.contributor.authorYuceyar, Ayse Nur
dc.contributor.authorBayam, Ece
dc.contributor.authorBademkiran, Fikret
dc.contributor.authorSirin, Hadiye
dc.contributor.authorSagduyu Kocaman, Ayse
dc.date.accessioned2019-10-27T21:42:45Z
dc.date.available2019-10-27T21:42:45Z
dc.date.issued2013
dc.departmentEge Üniversitesien_US
dc.description.abstractLithium is one of the first choice agents for long-term prophylaxis and the treatment of acute episodes of bipolar disorders. Because of its narrow therapeutic range and the common undesirable side effects, using lower lithium dosages with lower lithium serum levels are preferred treatment regimen especially for maintenance treatment. Concomitant drug using (especially neuroleptics), underlying infections and metabolic causes; such as dehydration and renal insufficiency take place in factors facilitating the development of toxicity. Lithium intoxication is distinguished in three different patterns as "acute", "chronic" and "toxicity during chronic use". Although patients with lithium poisoning may present with a variety of clinical manifestations, neurological symptoms appeared to dominate with a certain risk of persistency. In this report, four cases of lithium intoxication with neurological complications were presented with clinical and electrophysiological findings and lithium neurotoxicity was reviewed with recent literature.en_US
dc.identifier.endpage400en_US
dc.identifier.issn1302-1664
dc.identifier.issn1302-1664en_US
dc.identifier.issue2en_US
dc.identifier.startpage392en_US
dc.identifier.urihttps://hdl.handle.net/11454/46959
dc.identifier.volume30en_US
dc.identifier.wosWOS:000323600800019en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isotren_US
dc.publisherJournal Neurological Sciencesen_US
dc.relation.ispartofJournal of Neurological Sciences-Turkishen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectLithiumen_US
dc.subjecttoxicityen_US
dc.subjectneurotoxicityen_US
dc.subjectencephalopathyen_US
dc.subjectepilepsyen_US
dc.titleAcute Lithium Neurotoxicity: Clinical and Electrophysiological Evaluation of Four Casesen_US
dc.typeArticleen_US

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