Antioxidant defense systems in newborns undergoing phototherapy

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dc.contributor.authorAkisü M.
dc.contributor.authorYilmaz D.
dc.contributor.authorTüzün S.
dc.contributor.authorKültürsay N.
dc.date.accessioned2019-10-27T00:27:14Z
dc.date.available2019-10-27T00:27:14Z
dc.date.issued1999
dc.departmentEge Üniversitesien_US
dc.description.abstractThis paper was designed to investigate whether phototherapy is an oxidative stress in newborn infants undergoing phototherapy. A day-light continuous phototherapy was given to jaundiced 20 term and 16 preterm newborns for 72 hours. We measured serum vitamin E and the activities of red blood cell anti-oxidation enzymes (superoxide dismutase, catalase and glutathione peroxidase) before and after 72 h of phototherapy. Serum vitamin E levels were not different before and after 72 h of phototherapy in both preterm and term infants. In several studies, antioxidant enzyme activities have been shown to increase in response to oxidative stresses. In this study, however, the antioxidant enzyme activities in the hemolysate were similar before and at the end of the phototherapy in both preterm and full term. In conclusion, the results of our in vivo study do not confirm the thesis that phototherapy is an oxidative stress in newborn infants. Therefore, phototherapy would preferably seem to be safe and efficient method of treatment for all neonates presenting with hyperbilirubinemia. (Indian J Pediatr 1999; 66 : 651-655).en_US
dc.identifier.doi10.1007/BF02726243en_US
dc.identifier.endpage655en_US
dc.identifier.issn0019-5456
dc.identifier.issue5en_US
dc.identifier.pmid10798124en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage651en_US
dc.identifier.urihttps://doi.org/10.1007/BF02726243
dc.identifier.urihttps://hdl.handle.net/11454/23501
dc.identifier.volume66en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherThe Indian Journal of Pediatricsen_US
dc.relation.ispartofIndian Journal of Pediatricsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCatalaseen_US
dc.subjectGlutathione peroxidaseen_US
dc.subjectOxidant stressen_US
dc.subjectPhototherapyen_US
dc.titleAntioxidant defense systems in newborns undergoing phototherapyen_US
dc.typeArticleen_US

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