The role of posterior vitreous detachment and vitreomacular adhesion in patients with age-related macular degeneration

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dc.contributor.authorIlim O.
dc.contributor.authorAkkin C.
dc.contributor.authorOztas Z.
dc.contributor.authorNalcaci S.
dc.contributor.authorAfrashi F.
dc.contributor.authorDegirmenci C.
dc.contributor.authorMentes J.
dc.date.accessioned2019-10-27T08:04:06Z
dc.date.available2019-10-27T08:04:06Z
dc.date.issued2017
dc.departmentEge Üniversitesien_US
dc.description.abstractBACKGROUND AND OBJECTIVE: The aim of this study was to assess the prevalence of posterior vitreous detachment (PVD) and vitreoretinal interface in patients with age-related macular degeneration (AMD). PATIENTS AND METHODS: This clinical trial included 206 eyes of 138 patients who presented to the authors' clinic between January 2012 and November 2014. Patients were divided into three groups: 98 eyes of 67 patients with exudative AMD, 55 eyes of 36 patients with nonexudative AMD, and 53 eyes of 35 patients having no vitreoretinal disease. All patients underwent complete ocular examination, including best-corrected visual acuity, Goldmann applanation tonometry, fundus photography, spectral-domain optical coherence tomography, and B-mode ultrasonography at 6 months and 12 months after the initial examination. RESULTS: Total and partial PVD rates were significantly higher at baseline, 6 months, and 12 months in both exudative and nonexudative AMD groups when compared to the control group (Chi-square test, P = .006, P = .001, and P = .009, respectively). The prevalence of total PVD was significantly higher in nonexudative AMD, whereas partial PVD was higher in exudative AMD. The exudative AMD group reported significantly more VMA than the other two groups at baseline, 6 months, and 12 months (Chi-square test, P =.005, P = .003, and P = .019, respectively). CONCLUSION: This study indicates that the incidence of vitreoretinal interface abnormalities such as partial PVD and vitreomacular adhesion were higher in the exudative AMD group. It can be concluded that abnormal adhesive and tractional forces due to PVD may play a role in the progression of AMD.en_US
dc.identifier.doi10.3928/23258160-20170301-05en_US
dc.identifier.endpage229en_US
dc.identifier.issn2325-8160
dc.identifier.issue3en_US
dc.identifier.pmid28297034en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage223en_US
dc.identifier.urihttps://doi.org/10.3928/23258160-20170301-05
dc.identifier.urihttps://hdl.handle.net/11454/25465
dc.identifier.volume48en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSlack Incorporateden_US
dc.relation.ispartofOphthalmic Surgery Lasers and Imaging Retinaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.titleThe role of posterior vitreous detachment and vitreomacular adhesion in patients with age-related macular degenerationen_US
dc.typeArticleen_US

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