Holter ECG assessment of the effects of three different local anesthetic solutions on cardiovascular system in the sedated dental patients with coronary artery disease

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dc.contributor.authorZeytinoglu, Mert
dc.contributor.authorTuncay, Umit
dc.contributor.authorAkay, M. Cemal
dc.contributor.authorSoydan, Inan
dc.date.accessioned2019-10-27T22:09:09Z
dc.date.available2019-10-27T22:09:09Z
dc.date.issued2013
dc.departmentEge Üniversitesien_US
dc.description.abstractObjective: The purpose of the study is to compare the effects of lidocaine alone, epinephrine-combined lidocaine and prilocaine with octapressin on the cardiovascular system during minor oral surgery of sedated cardiac dental patients under local anesthesia. Methods: Connected to a Holter electrocardiogram (ECG) monitor for a total of 5 hours starting 1 hour before the procedure, twenty patients with high risk of coronary artery disease were included in the prospective cohort study. All the patients had three operations at 3 different appointments with at least one-week intervals and each operation was performed under local anesthesia achieved by 3.6 mL of 3% prilocaine with octapressin, 3.6 mL of 2% lidocaine with 1:80.000 epinephrine and 3.6 mL of 2% lidocaine without a vasoconstrictor. Data of the Holter ECG device assessed at the end of every hour and evaluated statistically. Repeated measures ANOVA, Friedman test, and Wilcoxon signed ranks test were used to perform statistical analysis. Results: Heart-rate showed significant differences between lidocaine with epinephrine and pure lidocaine in an hour following the injection (p<0.05 for all). Cardiac rhythm showed significant differences between prilocaine with octapressin and pure lidocaine at the second hour after its administration (p<0.05 for all). There were no significant differences between 3 local anesthetics in terms of ST segment deviation. Conclusion: In minor oral operation on the sedated patients with cardiac disease, the use of 3.6 mL or a less amount of local anesthetic injection containing epinephrine appears to be a predictable and safe method.en_US
dc.identifier.doi10.5152/akd.2013.146en_US
dc.identifier.endpage485en_US
dc.identifier.issn2149-2263
dc.identifier.issn2149-2271
dc.identifier.issue5en_US
dc.identifier.pmid23728226en_US
dc.identifier.startpage480en_US
dc.identifier.urihttps://doi.org/10.5152/akd.2013.146
dc.identifier.urihttps://hdl.handle.net/11454/49290
dc.identifier.volume13en_US
dc.identifier.wosWOS:000323324400016en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTurkish Soc Cardiologyen_US
dc.relation.ispartofAnatolian Journal of Cardiologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectMinor dental operationsen_US
dc.subjectlocal anestheticsen_US
dc.subjectcardiac diseasesen_US
dc.subjectHolter monitoringen_US
dc.titleHolter ECG assessment of the effects of three different local anesthetic solutions on cardiovascular system in the sedated dental patients with coronary artery diseaseen_US
dc.typeArticleen_US

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