Rationale, design, and methodology of the Evaluation of Perceptions, Knowledge, and Compliance with the Guidelines in Real Life Practice: A Survey on the Under-treatment of Hypercholesterolemia

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dc.contributor.authorDogan, Volkan
dc.contributor.authorBasaran, Ozcan
dc.contributor.authorOzlek, Bulent
dc.contributor.authorCelik, Oguzhan
dc.contributor.authorOzlek, Eda
dc.contributor.authorMert, Kadir Ugur
dc.contributor.authorRencuzogullari, Ibrahim
dc.contributor.authorMert, Gurbet Ozge
dc.contributor.authorDogan, Marwa Mouline
dc.contributor.authorBiteker, Murat
dc.contributor.authorKayikcioglu, Meral
dc.date.accessioned2019-10-27T10:46:17Z
dc.date.available2019-10-27T10:46:17Z
dc.date.issued2018
dc.departmentEge Üniversitesien_US
dc.description.abstractObjective: A wide gap exists between dyslipidemia guidelines and their implementation in the real world, which is primarily attributed to physician and patient compliance. The aim of this study is to determine physician and patient adherence to dyslipidemia guidelines and various influential factors. Methods: The Evaluation of Perceptions, Knowledge, and Compliance with the Guidelines in Real Life Practice: A Survey on the Under-treatment of Hypercholesterolemia (EPHESUS) trial (ClinicalTrials. gov number NCT02608645) will be an observational, multicenter, non-interventional study. The study targets enrollment of 2000 patients from 50 locations across Turkey. All of the data will be collected in a single visit and current clinical practice will be evaluated. A cross-sectional survey of public perception and knowledge of cholesterol treatment among Turkish adults will be performed. All consecutive patients admitted to cardiology clinics who are in the secondary prevention group (coronary heart disease, peripheral artery disease, atherosclerotic cerebrovascular disease) and who are in the high-risk primary prevention group (type 2 diabetes mellitus with no prior known coronary heart disease; patients who had markedly elevated single risk factors, in particular, cholesterol >8 mmol/L [>310 mg/dL], blood pressure >= 180/110 mmHg, a calculated Systematic Coronary Risk Evaluation [SCORE] >= 5%, or <10% 10-year risk of fatal cardiovascular disease) will be included. Demographic, lifestyle, medical, and therapeutic data will be collected with a survey designed for the study. Conclusion: The EPHESUS registry will be the largest study conducted in Turkey evaluating the adherence to dyslipidemia guidelines both in secondary and high-risk primary prevention patients.en_US
dc.identifier.doi10.5543/tkda.2017.73861en_US
dc.identifier.endpage53en_US
dc.identifier.issn1016-5169
dc.identifier.issue1en_US
dc.identifier.pmid29339691en_US
dc.identifier.startpage47en_US
dc.identifier.urihttps://doi.org/10.5543/tkda.2017.73861
dc.identifier.urihttps://hdl.handle.net/11454/31277
dc.identifier.volume46en_US
dc.identifier.wosWOS:000429103400008en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTurkish Soc Cardiologyen_US
dc.relation.ispartofTurk Kardiyoloji Dernegi Arsivi-Archives of the Turkish Society of Cardiologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectLipiden_US
dc.subjectstatin therapyen_US
dc.subjectTurkeyen_US
dc.titleRationale, design, and methodology of the Evaluation of Perceptions, Knowledge, and Compliance with the Guidelines in Real Life Practice: A Survey on the Under-treatment of Hypercholesterolemiaen_US
dc.typeArticleen_US

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