Algorithms for scheduling of chemotherapy plans

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dc.contributor.authorSevinc, Suleyman
dc.contributor.authorSanli, Ulus Ali
dc.contributor.authorGoker, Erdem
dc.date.accessioned2019-10-27T22:07:01Z
dc.date.available2019-10-27T22:07:01Z
dc.date.issued2013
dc.departmentEge Üniversitesien_US
dc.description.abstractChemotherapy is used to control and cure cancer by using drugs to destroy cancer cells. Treatment schedules for chemotherapy may vary depending on the type of cancer, the goals of treatment, the type of chemotherapy and the patient's state of health. Chemotherapy is usually given in cycles of a treatment-period followed by a rest-period. An oncologist decides the choice of a particular regimen; however, modifications to drug dose and schedule are often necessary because of variabilities in the health of an individual patient. Therefore an orderly execution of chemotherapy regimens requires management, scheduling and allocation of the resources available. Chemotherapy scheduling is an optimization problem. In this paper, a two-phase approach has been adopted to deal with the problem. An adaptive negative-feedback scheduling algorithm is proposed for the first phase to control the load on the system. Two heuristics based on the 'Multiple Knapsack Problem' have been evaluated for the second phase to assign patients to specific infusion seats. The overall design has been put to test at a local chemotherapy center and has yielded good results for patient waiting times, orderly execution of chemotherapy regimen and utilization of infusion chairs. (C) 2013 Elsevier Ltd. All rights reserved.en_US
dc.identifier.doi10.1016/j.compbiomed.2013.10.012en_US
dc.identifier.endpage2109en_US
dc.identifier.issn0010-4825
dc.identifier.issn1879-0534
dc.identifier.issue12en_US
dc.identifier.pmid24290927en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage2103en_US
dc.identifier.urihttps://doi.org/10.1016/j.compbiomed.2013.10.012
dc.identifier.urihttps://hdl.handle.net/11454/48933
dc.identifier.volume43en_US
dc.identifier.wosWOS:000329413800014en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherPergamon-Elsevier Science Ltden_US
dc.relation.ispartofComputers in Biology and Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectChemotherapy regimenen_US
dc.subjectChemotherapy schedulingen_US
dc.subjectChemotherapy algorithmsen_US
dc.subjectResource allocationen_US
dc.subjectChemotherapy management softwareen_US
dc.subjectAdaptive schedulingen_US
dc.titleAlgorithms for scheduling of chemotherapy plansen_US
dc.typeArticleen_US

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