Dynamic computed tomography in solitary pulmonary nodules

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dc.contributor.authorBayraktaroglu, Selen
dc.contributor.authorSavas, Recep
dc.contributor.authorBasoglu, Oezen Kacmaz
dc.contributor.authorCakan, Alparslan
dc.contributor.authorMogulkoc, Nesrin
dc.contributor.authorCagirici, Ufuk
dc.contributor.authorAlper, Huedaver
dc.date.accessioned2019-10-27T19:55:07Z
dc.date.available2019-10-27T19:55:07Z
dc.date.issued2008
dc.departmentEge Üniversitesien_US
dc.description.abstractObjective: To evaluate the utility of dynamic computed tomography (CT) imaging in the management of solitary pulmonary nodules. Methods: We examined solitary pulmonary nodules in 45 patients. The nodules included in the study were solid, homogenous, and spherical or oval-shaped in precontrast images. Nodules that had calcification or fat density were excluded from the study. We were not able to obtain clinical or pathological diagnosis of the nodules in 23 patients, and we excluded these patients from statistical analysis. Patients were examined with 2-mm collimation and I-mm reconstruction interval. Computed tomography examinations were done before and after injection of contrast material. Computed tomography scans of the nodule were obtained in the first, second, third, fourth, and fifth minutes after contrast injection. Results: The malignancy prevalence was 40%. The mean enhancement of malignant nodules were significantly higher than the benign ones. Also, the peak attenuation value obtained after the administration of contrast material was 82.44 +/- 19.56 HU in malignant lesions and 54 +/- 23.10 HU in benign ones, with statistical significance (P = 0.006). Using enhancement values greater than 15 HU as a threshold for malignancy, the calculated sensitivity, specificity, positive and negative predictive values, and accuracy of the dynamic CT examination were 100%, 69.2%, 69.2%, 100%, and 81%, respectively. Conclusion: Dynamic CT imaging demonstrates significantly greater enhancement in malignant nodules than in benign ones. Lung nodule enhancement of 15 HU or less strongly indicates benignity.en_US
dc.identifier.doi10.1097/RCT.0b013e318136e29den_US
dc.identifier.endpage227en_US
dc.identifier.issn0363-8715
dc.identifier.issue2en_US
dc.identifier.pmid18379306en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage222en_US
dc.identifier.urihttps://doi.org/10.1097/RCT.0b013e318136e29d
dc.identifier.urihttps://hdl.handle.net/11454/40632
dc.identifier.volume32en_US
dc.identifier.wosWOS:000254683500011en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherLippincott Williams & Wilkinsen_US
dc.relation.ispartofJournal of Computer Assisted Tomographyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.titleDynamic computed tomography in solitary pulmonary nodulesen_US
dc.typeArticleen_US

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