Combination Therapy With Verapamil and Nitrendipine In Patients With Hypertension

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dc.contributor.authorNalbantgil, I
dc.contributor.authorOnder, R
dc.contributor.authorKiliccioglu, B
dc.contributor.authorTurkoglu, C
dc.date.accessioned2019-10-27T11:36:00Z
dc.date.available2019-10-27T11:36:00Z
dc.date.issued1993
dc.departmentEge Üniversitesien_US
dc.description.abstractForty patients with mild to moderate hypertension were divided into two groups, 20 patients (group A) received 240 mg verapamil and 20 patients (group 8) received 20 mg nitrendipine dally during the first six weeks. During the second six weeks, all 40 patients were given 10 mg nitrendipine plus 120 mg verapamil. After the combination therapy, group B received verapamil, 240 mg and group A nitrendipine 20 mg for a further period of six weeks. When verapamil and nitrendipine were used alone, BP decreased significantly in each group. However, BP decreased more when the combination therapy was used and increased when the treatment was changed to single drug therapy from the two-drug combination. In addition, side-effects were three to four times fewer during the combination therapy. It is concluded that the combination of two different calcium antagonists in the treatment of hypertension provides a new dimension to therapy.en_US
dc.identifier.endpage308en_US
dc.identifier.issn0950-9240
dc.identifier.issue3en_US
dc.identifier.pmid8345499en_US
dc.identifier.startpage305en_US
dc.identifier.urihttps://hdl.handle.net/11454/33835
dc.identifier.volume7en_US
dc.identifier.wosWOS:A1993LG99000015en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherStockton Pressen_US
dc.relation.ispartofJournal of Human Hypertensionen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.titleCombination Therapy With Verapamil and Nitrendipine In Patients With Hypertensionen_US
dc.typeArticleen_US

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