Comprehensive Analysis of Severe Viral Infections of Respiratory Tract admitted to PICUs during the Winter Season in Turkey

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dc.contributor.authorKockuzu, Esra
dc.contributor.authorBayrakci, Benan
dc.contributor.authorKesici, Selman
dc.contributor.authorCitak, Agop
dc.contributor.authorKarapinar, Bulent
dc.contributor.authorEmeksiz, Serhat
dc.contributor.authorTalip, Mey
dc.date.accessioned2020-12-01T12:09:35Z
dc.date.available2020-12-01T12:09:35Z
dc.date.issued2019
dc.departmentEge Üniversitesien_US
dc.descriptionOTO, ARZU/0000-0003-0229-2759; Sevketoglu, Esra/0000-0002-8330-2877;en_US
dc.description.abstractObjectives:To analyze the course of seasonal viral infections of respiratory tract in patients hospitalized in pediatric intensive care units (PICU) of 16 centers in Turkey. Materials and methods: It is a retrospective, observational, and multicenter study conducted in 16 tertiary PICUs in Turkey includes a total of 302 children with viral cause in the nasal swab which required PICU admission with no interventions. Results: Median age of patients was 12 months. Respiratory syncytial virus (RSV) was more common in patients over one year of age whereas influenza, human Bocavirus in patients above a year of age was more common (p <0.05). Clinical presentations influencing mortality were neurologic symptoms, tachycardia, hypoxia, hypotension, elevated lactate, and acidosis. the critical pH value related with mortality was <= 7.10, and critical PCO2 >= 60 mm Hg. Conclusion: Our findings demonstrate that patients with neurological symptoms, tachycardia, hypoxia, hypotension, acidosis, impaired liver, and renal function at the time of admission exhibit more severe mortal progressions. Presence of acidosis and multiorgan failure was found to be predictor for mortality. Knowledge of clinical presentation and age-related variations among seasonal viruses may give a clue about severe course and prognosis. By presenting the analyzed data of 302 PICU admissions, current study reveals severity of viral respiratory tract infections and release tips for handling them.en_US
dc.identifier.doi10.5005/jp-journals-10071-23177
dc.identifier.endpage269en_US
dc.identifier.issn0972-5229
dc.identifier.issn1998-359X
dc.identifier.issue6en_US
dc.identifier.pmid31435144en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage263en_US
dc.identifier.urihttps://doi.org/10.5005/jp-journals-10071-23177
dc.identifier.urihttps://hdl.handle.net/11454/63504
dc.identifier.volume23en_US
dc.identifier.wosWOS:000496521400006en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherJaypee Brothers Medical Publishers Pvt Ltden_US
dc.relation.ispartofIndian Journal of Critical Care Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectMortalityen_US
dc.subjectMulti organ failureen_US
dc.subjectPediatric intensive care uniten_US
dc.subjectSeasonalen_US
dc.subjectVirusesen_US
dc.titleComprehensive Analysis of Severe Viral Infections of Respiratory Tract admitted to PICUs during the Winter Season in Turkeyen_US
dc.typeArticleen_US

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