Effect of metabolic control on cognitive functions in children and adolescents with type 1 diabetes mellitus

Basit Öğe Kaydı
dc.authoridEr, Eren/0000-0003-4770-0365
dc.authorscopusid58245798000
dc.authorscopusid57220119294
dc.authorscopusid57216201215
dc.authorscopusid57202022119
dc.authorscopusid57216348295
dc.authorscopusid36657286700
dc.authorscopusid24402424500
dc.authorwosidEr, Eren/HNS-7811-2023
dc.contributor.authorKar, Seyma
dc.contributor.authorEr, Eren
dc.contributor.authorAta, Aysun
dc.contributor.authorInal-Kaleli, Ipek
dc.contributor.authorOzcan, Tugce
dc.contributor.authorKose, Sezen
dc.contributor.authorOzbaran, Burcu
dc.date.accessioned2024-08-25T18:36:00Z
dc.date.available2024-08-25T18:36:00Z
dc.date.issued2023
dc.departmentEge Üniversitesien_US
dc.description.abstractObjectives: Neurocognitive functions of children with type 1 diabetes mellitus (T1D) are reported to be poorer than those of healthy peers. The aim was to investigate the effects of age of onset of diabetes, metabolic control, and type of insulin regimen on neurocognitive functions in children and adolescents with T1D.Methods: Forty-seven children aged 6-18 years, with T1D for at least five years, were included. Children with a known psychiatric disorder or chronic diseases other than T1D were excluded. Intelligence via the Wechsler children's intelligence scale (WISC-R), short-term memory via the audio-auditory digits form B (GISD-B) test, visual motor perception via the Bender Gestalt test, and attention via the Moxo continuous attention and performance test, timing, hyperactivity, and impulsivity (Moxo-dCPT) were assessed.Results: Compared with the T1D group, healthy controls had higher scores in terms of verbal intelligence quotient (IQ), performance IQ, and total IQ mean scores on WISC-R (p=0.01, p=0.05 and p=0.01, respectively). On the MOXO-dCPT test, the T1D group had higher impulsivity compared to the control group (p=0.04). Verbal IQ was better in the moderate control group than in the poorer metabolic control (p=0.01). Patients with no history of diabetic ketoacidosis (DKA) had higher performance, verbal and total intelligence scores than the group with history of DKA.Conclusions: Poor metabolic control and a history of DKA in children with T1D adversely affected neurocognitive functions. It would be beneficial to consider the assessment of neurocognitive functions in T1D and to take the necessary precautions in follow-up.en_US
dc.description.sponsorshipUniversity of Ege 'Scientific Research Projects Committee' [TTU-2020-20979]en_US
dc.description.sponsorshipThis study was supported by the University of Ege 'Scientific Research Projects Committee'by Project code TTU-2020-20979.en_US
dc.identifier.doi10.1515/jpem-2023-0027
dc.identifier.issn0334-018X
dc.identifier.issn2191-0251
dc.identifier.pmid37146253en_US
dc.identifier.scopus2-s2.0-85159062714en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.urihttps://doi.org/10.1515/jpem-2023-0027
dc.identifier.urihttps://hdl.handle.net/11454/100495
dc.identifier.wosWOS:000982259000001en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWalter De Gruyter Gmbhen_US
dc.relation.ispartofJournal of Pediatric Endocrinology & Metabolismen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmz20240825_Gen_US
dc.subjectcognitive functionen_US
dc.subjecthyperglycemiaen_US
dc.subjecthypoglycemiaen_US
dc.subjecttype 1 diabetesen_US
dc.subjectComplicationsen_US
dc.subjectImpairmenten_US
dc.subjectAdultsen_US
dc.titleEffect of metabolic control on cognitive functions in children and adolescents with type 1 diabetes mellitusen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu