Comparison of the proportion dilution method and E-test for ofloxacin and ciprofloxacin susceptibility testing of mycobacterium tuberculosis [Mycobacterium tuberculosis suşlarinda ofloksasi·n ve si·profloksasi·n duyarliliginin saptanmasinda standart oranti di·lüsyon i·le E-test yöntemleri·ni·n karşilaştirilmasi]
dc.contributor.author | Çavuşoglu C. | |
dc.contributor.author | Çiçek Saydam C. | |
dc.contributor.author | Burhanoglu D. | |
dc.contributor.author | Özkalay N. | |
dc.contributor.author | Özkaya D. | |
dc.contributor.author | Özçam H. | |
dc.contributor.author | Bilgiç A. | |
dc.date.accessioned | 2019-10-27T00:24:47Z | |
dc.date.available | 2019-10-27T00:24:47Z | |
dc.date.issued | 2001 | |
dc.department | Ege Üniversitesi | en_US |
dc.description.abstract | In this study, the antibacterial activities of ofloxacin and ciprofloxacin on 100 clinical isolates of Mycobacterium tuberculosis were investigated by using standard proportion dilution method and E-test. The sensitivities of the isolates to conventional antibiotics (isoniazide, ethambutol, rifampin, streptomycin) were determined by Bactec system and 6 were found resistant to isoniazide, while 4 strains showed multi-drug resistance. All of the 10 resistant strains and 88 of 90 sensitive strains (98%) were found susceptible to ofloxacin and ciprofloxacin by both proportion dilution method and E-test. Two of the isolates (2%) which were susceptible to first choise antituberculous drugs, were found resistant to ofloxacin and ciprofloxacin by both of the methods. As a result, the accordance between E-test and standard proportion dilution method was detected as 100 percent. | en_US |
dc.identifier.endpage | 511 | en_US |
dc.identifier.issn | 0374-9096 | |
dc.identifier.issn | 0374-9096 | en_US |
dc.identifier.issue | 4 | en_US |
dc.identifier.scopusquality | Q4 | en_US |
dc.identifier.startpage | 505 | en_US |
dc.identifier.uri | https://hdl.handle.net/11454/23138 | |
dc.identifier.volume | 35 | en_US |
dc.indekslendigikaynak | Scopus | en_US |
dc.language.iso | tr | en_US |
dc.relation.ispartof | Mikrobiyoloji Bulteni | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | Ciprofloxacin | en_US |
dc.subject | Mycobacterium tuberculosis | en_US |
dc.subject | Ofloxacin | en_US |
dc.subject | Susceptibility | en_US |
dc.title | Comparison of the proportion dilution method and E-test for ofloxacin and ciprofloxacin susceptibility testing of mycobacterium tuberculosis [Mycobacterium tuberculosis suşlarinda ofloksasi·n ve si·profloksasi·n duyarliliginin saptanmasinda standart oranti di·lüsyon i·le E-test yöntemleri·ni·n karşilaştirilmasi] | en_US |
dc.type | Article | en_US |