Comparison of the proportion dilution method and E-test for ofloxacin and ciprofloxacin susceptibility testing of mycobacterium tuberculosis [Mycobacterium tuberculosis suşlarinda ofloksasi·n ve si·profloksasi·n duyarliliginin saptanmasinda standart oranti di·lüsyon i·le E-test yöntemleri·ni·n karşilaştirilmasi]

dc.contributor.authorÇavuşoglu C.
dc.contributor.authorÇiçek Saydam C.
dc.contributor.authorBurhanoglu D.
dc.contributor.authorÖzkalay N.
dc.contributor.authorÖzkaya D.
dc.contributor.authorÖzçam H.
dc.contributor.authorBilgiç A.
dc.date.accessioned2019-10-27T00:24:47Z
dc.date.available2019-10-27T00:24:47Z
dc.date.issued2001
dc.departmentEge Üniversitesien_US
dc.description.abstractIn this study, the antibacterial activities of ofloxacin and ciprofloxacin on 100 clinical isolates of Mycobacterium tuberculosis were investigated by using standard proportion dilution method and E-test. The sensitivities of the isolates to conventional antibiotics (isoniazide, ethambutol, rifampin, streptomycin) were determined by Bactec system and 6 were found resistant to isoniazide, while 4 strains showed multi-drug resistance. All of the 10 resistant strains and 88 of 90 sensitive strains (98%) were found susceptible to ofloxacin and ciprofloxacin by both proportion dilution method and E-test. Two of the isolates (2%) which were susceptible to first choise antituberculous drugs, were found resistant to ofloxacin and ciprofloxacin by both of the methods. As a result, the accordance between E-test and standard proportion dilution method was detected as 100 percent.en_US
dc.identifier.endpage511en_US
dc.identifier.issn0374-9096
dc.identifier.issn0374-9096en_US
dc.identifier.issue4en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage505en_US
dc.identifier.urihttps://hdl.handle.net/11454/23138
dc.identifier.volume35en_US
dc.indekslendigikaynakScopusen_US
dc.language.isotren_US
dc.relation.ispartofMikrobiyoloji Bultenien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCiprofloxacinen_US
dc.subjectMycobacterium tuberculosisen_US
dc.subjectOfloxacinen_US
dc.subjectSusceptibilityen_US
dc.titleComparison of the proportion dilution method and E-test for ofloxacin and ciprofloxacin susceptibility testing of mycobacterium tuberculosis [Mycobacterium tuberculosis suşlarinda ofloksasi·n ve si·profloksasi·n duyarliliginin saptanmasinda standart oranti di·lüsyon i·le E-test yöntemleri·ni·n karşilaştirilmasi]en_US
dc.typeArticleen_US

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