Comparison of the proportion dilution method and E-test for ofloxacin and ciprofloxacin susceptibility testing of mycobacterium tuberculosis [Mycobacterium tuberculosis suşlarinda ofloksasi·n ve si·profloksasi·n duyarliliginin saptanmasinda standart oranti di·lüsyon i·le E-test yöntemleri·ni·n karşilaştirilmasi]
Küçük Resim Yok
Tarih
2001
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
In this study, the antibacterial activities of ofloxacin and ciprofloxacin on 100 clinical isolates of Mycobacterium tuberculosis were investigated by using standard proportion dilution method and E-test. The sensitivities of the isolates to conventional antibiotics (isoniazide, ethambutol, rifampin, streptomycin) were determined by Bactec system and 6 were found resistant to isoniazide, while 4 strains showed multi-drug resistance. All of the 10 resistant strains and 88 of 90 sensitive strains (98%) were found susceptible to ofloxacin and ciprofloxacin by both proportion dilution method and E-test. Two of the isolates (2%) which were susceptible to first choise antituberculous drugs, were found resistant to ofloxacin and ciprofloxacin by both of the methods. As a result, the accordance between E-test and standard proportion dilution method was detected as 100 percent.
Açıklama
Anahtar Kelimeler
Ciprofloxacin, Mycobacterium tuberculosis, Ofloxacin, Susceptibility
Kaynak
Mikrobiyoloji Bulteni
WoS Q Değeri
Scopus Q Değeri
Q4
Cilt
35
Sayı
4
