Serum resistin level: as a predictor of atrial fibrillation after coronary artery bypass graft surgery

Basit Öğe Kaydı
dc.contributor.authorGungor, Hasan
dc.contributor.authorAyik, Mehmet Fatih
dc.contributor.authorKirilmaz, Bahadir
dc.contributor.authorErtugay, Serkan
dc.contributor.authorGul, Ilker
dc.contributor.authorYildiz, Bekir Serhat
dc.contributor.authorNalbantgil, Sanem
dc.contributor.authorZoghi, Mehdi
dc.date.accessioned2019-10-27T21:35:45Z
dc.date.available2019-10-27T21:35:45Z
dc.date.issued2011
dc.departmentEge Üniversitesien_US
dc.description.abstractAim Atrial fibrillation (AF) is the most common arrhythmia with an incidence of 25-40%, after coronary artery bypass grafting (CABG). Resistin is a newly identified adipocyte-secreted hormone belonging to a cysteine-rich protein family. This study examined the relation of preoperative and postoperative early serum resistin level, which can play an important role as an inflammatory marker to predict AF after CABG. Methods We prospectively analyzed 40 consecutive patients (mean age, 59.2+10.3 years; 31 men and nine women) who were undergoing CABG between September and November 2009 at our department. Blood samples were taken to examine quantities of resistin level, the day before surgery and on the 24th hour in the intensive care unit. Results The incidence of AF was 25% (n=10, 2.2+1.1 days, 1.2+0.4 episodes). Preoperative resistin level was higher in the AF group (10.6+3.3 vs. 9.1+4.5 ng/ml, P=0.33), but it was not statistically significant. Postoperative resistin level was significantly higher in the AF group (27.4+8.4 vs. 17.9+9.1 ng/ml, P=0.012) compared with the sinus rhythm group. Resistin levels significantly increased after the surgery in both groups [9.1+4.5 vs. 17.9+9.1 ng/ml, P<0.001 (sinus rhythm group) and 10.6+3.3 vs. 27.4+8.4 ng/ml, P<0.001 (AF group)]. Conclusion Patients with an elevated postoperative resistin level may have high risk for AF after CABG. This intervention targeting inflammation might help reduce the incidence of AF. Coron Artery Dis 22:484-490 (C) 2011 Wolters Kluwer Health vertical bar Lippincott Williams & Wilkins.en_US
dc.identifier.doi10.1097/MCA.0b013e32834b67bben_US
dc.identifier.endpage490en_US
dc.identifier.issn0954-6928
dc.identifier.issue7en_US
dc.identifier.pmid21915052en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage484en_US
dc.identifier.urihttps://doi.org/10.1097/MCA.0b013e32834b67bb
dc.identifier.urihttps://hdl.handle.net/11454/45922
dc.identifier.volume22en_US
dc.identifier.wosWOS:000295621500006en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherLippincott Williams & Wilkinsen_US
dc.relation.ispartofCoronary Artery Diseaseen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectatrial fibrillationen_US
dc.subjectcoronary artery bypass graft surgeryen_US
dc.subjectinflammationen_US
dc.subjectresistinen_US
dc.titleSerum resistin level: as a predictor of atrial fibrillation after coronary artery bypass graft surgeryen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu