Immunohistochemical and Histopathological Evaluation of 2,4-Dichlorophenoxyacetic Acid-Induced Changes in Rat Kidney Cortex

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dc.contributor.authorUyanikgil, Yigit
dc.contributor.authorAtes, Utku
dc.contributor.authorBaka, Meral
dc.contributor.authorBicer, Songuel
dc.contributor.authorOztas, Ebru
dc.contributor.authorErgen, Guersel
dc.date.accessioned2019-10-27T20:51:22Z
dc.date.available2019-10-27T20:51:22Z
dc.date.issued2009
dc.departmentEge Üniversitesien_US
dc.description7th National Congress of Histology and Embryology -- JUN 27-30, 2006 -- Malatya, TURKEYen_US
dc.description.abstractThis study aims to investigate the effect of 2,4-dichlorophenoxyacetic acid (2,4-D) on rat kidney cortex histology. Oral exposure of rats to 2,4-D for 28 days resulted in decreases in body weight gain and kidney weight. Histological examination showed degeneration in renal corpuscles and podocytes; vacuolization in the glomerulus with disintegration of the basal membrane; tissue edema; vacuolization, cystic dilation and invagination of the basal laminae in the tubular structures; dilation and congestion in renal corpuscular vessels and marked decrease in glomerular and stromal fibronectin reaction; suggesting that subacute 2,4-D administration induces dose-dependent histopathological degenerative effects in rat kidney cortex.en_US
dc.identifier.doi10.1007/s00128-009-9689-5en_US
dc.identifier.endpage755en_US
dc.identifier.issn0007-4861
dc.identifier.issue6en_US
dc.identifier.pmid19277441en_US
dc.identifier.startpage749en_US
dc.identifier.urihttps://doi.org/10.1007/s00128-009-9689-5
dc.identifier.urihttps://hdl.handle.net/11454/43106
dc.identifier.volume82en_US
dc.identifier.wosWOS:000264832600021en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofBulletin of Environmental Contamination and Toxicologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectHerbicideen_US
dc.subject2,4-Den_US
dc.subjectHistopathologyen_US
dc.subjectKidneyen_US
dc.subjectRaten_US
dc.titleImmunohistochemical and Histopathological Evaluation of 2,4-Dichlorophenoxyacetic Acid-Induced Changes in Rat Kidney Cortexen_US
dc.typeArticleen_US

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