The longitudinal evaluation of COVID-19 in pediatric patients and the impact of delta variant

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dc.authoridGüner Özenen, Gizem/0000-0002-9725-7501
dc.authoridYazıcı Özkaya, Pınar/0000-0002-1209-2534
dc.authorscopusid57200551951
dc.authorscopusid38061964200
dc.authorscopusid57222317768
dc.authorscopusid57222327020
dc.authorscopusid57221502271
dc.authorscopusid57223005975
dc.authorscopusid41662339000
dc.authorwosidGüner Özenen, Gizem/ABG-2316-2021
dc.authorwosidYazıcı Özkaya, Pınar/GWQ-8519-2022
dc.contributor.authorArslan, Asli
dc.contributor.authorBal, Zumrut Sahbudak
dc.contributor.authorArslan, Sema Yildirim
dc.contributor.authorBilen, Nimet Melis
dc.contributor.authorOzenen, Gizem Guner
dc.contributor.authorOzkaya, Pinar Yazici
dc.contributor.authorYurtseven, Ali
dc.date.accessioned2024-08-25T18:32:25Z
dc.date.available2024-08-25T18:32:25Z
dc.date.issued2022
dc.departmentEge Üniversitesien_US
dc.description.abstractBackground Pediatric patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) displayed milder symptoms than adults. However, they play an important role in case numbers and virus transmission. Therefore, we aimed to determine the epidemiological features of all pediatric patients infected with SARS-CoV-2 and put forth case numbers longitudinally throughout the delta variant dominant period. Methods A retrospective study was conducted at a university hospital and included patients between 0 and18 years old with a SARS-CoV-2 polymerase chain reaction (PCR) positive result, including inpatients and outpatients. Epidemiological and clinical features were recorded from electronic files, and telephone visits were performed between March 2020 and December 2021. Results During the study period, 3175 coronavirus disease 2019 (COVID-19) pediatric patients were admitted to our hospital with a mean age of 10.61 +/- 4.6 years. Of the 1815 patients who could be interviewed, 85.7% reported at least one symptom. Before the delta variant period, 0-4 years aged children were more commonly infected, while school-aged children and adolescents were more common, and the rate of pediatric cases to all COVID-19 cases increased to 35.8% after the delta variant became dominant. Symptomatic cases were significantly higher before the delta variant (87.8% vs. 84.06%, p = 0.016). The hospitalization rate was higher before the delta variant (p < 0.001), whereas PICU admission showed no statistical difference. Conclusions The frequency of school-aged children and adolescents raised with the impact of both school openings and the delta variant, and the rate of pediatric cases increased in total COVID-19 patient numbers.en_US
dc.identifier.doi10.1093/tropej/fmac115
dc.identifier.issn0142-6338
dc.identifier.issn1465-3664
dc.identifier.issue1en_US
dc.identifier.pmid36611014en_US
dc.identifier.scopus2-s2.0-85145966555en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.urihttps://doi.org/10.1093/tropej/fmac115
dc.identifier.urihttps://hdl.handle.net/11454/100223
dc.identifier.volume69en_US
dc.identifier.wosWOS:000908343300002en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherOxford Univ Pressen_US
dc.relation.ispartofJournal of Tropical Pediatricsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmz20240825_Gen_US
dc.subjectSARS-CoV-2en_US
dc.subjectdelta varianten_US
dc.subjectpediatric patientsen_US
dc.subjectepidemiologyen_US
dc.subjectClinical-Outcomesen_US
dc.subjectUnited-Statesen_US
dc.subjectChildrenen_US
dc.subjectSars-Cov-2en_US
dc.subjectDiseaseen_US
dc.titleThe longitudinal evaluation of COVID-19 in pediatric patients and the impact of delta varianten_US
dc.typeArticleen_US

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