Evaluation of ocular surface and meibomian glands in patients with uveitis related to oligoarticular juvenile idiopathic arthritis

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dc.contributor.authorDegirmenci, Cumali
dc.contributor.authorPalamar, Melis
dc.contributor.authorGuven Yilmaz, Suzan
dc.contributor.authorAtes, Halil
dc.date.accessioned2020-12-01T11:59:13Z
dc.date.available2020-12-01T11:59:13Z
dc.date.issued2020
dc.departmentEge Üniversitesien_US
dc.description.abstractPurpose To evaluate ocular surface changes and meibomian gland scores in patients with oligoarticular juvenile idiopathic arthritis. Materials and methods This prospective study was conducted at Ege University School of Medicine, Department of Ophthalmology. A total of 34 eyes of 17 patients with oligoarticular juvenile idiopathic arthritis and 30 right eyes of 30 age and gender-matched healthy subjects were included. Besides ophthalmic examination Schirmer 1 test, tear film break up time, Oxford staining scale and meibography were performed. Results There was no statistically significant differences between groups in terms of age, mean intraocular pressure, mean Schirmer 1 test value, tear film break up time and Oxford staining score. the median upper and lower eyelid meiboscore were 1 +/- 0.60 (IQR = 1), and 0 +/- 0.34 (IQR = 0) in Group 1, and they were 1 +/- 0.56 (IQR = 0), 1 +/- 0.12 (IQR = 1) in Group 2. Also, mean upper and lower meiboscores were statistically similar (pvalues 0.068 and 0.545, respectively). However, the median total meiboscore was 1 +/- 0.42 (IQR = 1) in Group 1 and 1 +/- 0.66 (IQR = 1) in Group 2. the difference was statistically significant (p = 0.041). Conclusion Aqueous-deficient dry eye is a well-known condition in patients with rheumatologic diseases. However, evaporative dry eye and meibomian glands were not studied earlier. the current study demonstrated that total meiboscores of oligoarticular juvenile idiopathic arthritis patients are higher than normal subjects, which indicates a possible evaporative dry eye tendency in this entity.en_US
dc.identifier.doi10.1007/s10792-020-01357-wen_US
dc.identifier.endpage1867en_US
dc.identifier.issn0165-5701
dc.identifier.issn1573-2630
dc.identifier.issue7en_US
dc.identifier.pmid32270334en_US
dc.identifier.scopus2-s2.0-85083053962en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage1863en_US
dc.identifier.urihttps://doi.org/10.1007/s10792-020-01357-w
dc.identifier.urihttps://hdl.handle.net/11454/62205
dc.identifier.volume40en_US
dc.identifier.wosWOS:000544253500029en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofInternational Ophthalmologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectDry eyeen_US
dc.subjectJuvenile idiopathic arthritisen_US
dc.subjectMeibographyen_US
dc.subjectOcular surfaceen_US
dc.titleEvaluation of ocular surface and meibomian glands in patients with uveitis related to oligoarticular juvenile idiopathic arthritisen_US
dc.typeArticleen_US

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