COVID-19 and Vaccination Status in Lysosomal Storage Diseases: A Single-Center Experience
Küçük Resim Yok
Tarih
2023
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
AVES
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Objective: Coronavirus disease 2019 (COVID-19) causes significant morbidity and mortality in individuals with chronic disease. There is not enough information about the course of corona-virus disease in lysosomal storage diseases. This study aimed to evaluate coronavirus disease vaccination status and the impact of coronavirus disease on lysosomal storage disease. Materials and Methods: The study included 87 lysosomal storage disease patients. The patients’ diagnoses were Gaucher, mucopolysaccharidosis I, II, IVA, VI, VII, Fabry, and Pompe. A questionnaire assessing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) exposure, coronavirus disease symptoms, and vaccine status was administered in person or by phone calls. Results: The number of coronavirus disease positive patients was 8 (9.1%). Only 2 patients were treated in the intensive care unit. Other coronavirus disease patients had mild symptoms and stayed in-home quarantine. Patients over 12 years of age could receive a COVID-19 vaccine. 63.5% of those aged ?12 years were vaccinated. Conclusion: Lysosomal storage disease patients did not have an increased risk of COVID-19 compared to the healthy population, despite the chronic inflammatory disease. Vaccination of lysosomal storage disease patients will be protective against severe coronavirus disease. © 2023, AVES. All rights reserved.
Açıklama
Anahtar Kelimeler
COVID-19, fabry, Gaucher, inherited metabolic diseases, lysosomal storage diseases, SARS-CoV-2, coronavac, favipiravir, immunoglobulin, steroid, tenofovir, adolescent, adult, anosmia, Article, child, clinical article, coronavirus disease 2019, diabetes mellitus, Fabry disease, female, Gaucher disease, headache, hospitalization, human, hypertension, inflammatory disease, intensive care unit, leukopenia, liver disease, lung disease, lysosome storage disease, male, morbidity, mortality, mucopolysaccharidosis, nose smear, obesity, pneumonia, polymerase chain reaction, questionnaire, sore throat, thrombocytopenia, vaccination
Kaynak
Turkish Archives of Pediatrics
WoS Q Değeri
Scopus Q Değeri
Q3
Cilt
58
Sayı
3
