Electrodiagnostic pattern approach for childhood polyneuropathies

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dc.contributor.authorPolat, Muzaffer
dc.contributor.authorTekgul, Hasan
dc.contributor.authorKilincer, Ahmet
dc.contributor.authorTosun, Ayse
dc.contributor.authorTerlemez, Semiha
dc.contributor.authorSerdaroglu, Gul
dc.contributor.authorUludag, Burhanettin
dc.contributor.authorGokben, Sarenur
dc.date.accessioned2019-10-27T19:18:10Z
dc.date.available2019-10-27T19:18:10Z
dc.date.issued2006
dc.departmentEge Üniversitesien_US
dc.description.abstractElectrophysiologic studies play a key role in the detection and characterization of the pattern in childhood polyneuropathies. In this study, the etiologic profile of 74 children with polyneuropathy was prospectively evaluated based on the electrophysiologic studies. Five electrodiagnostic patterns were identified in the cohort: (1) acute axonal polyneuropathy (n: 32, 43%); (2) chronic axonal polyneuropathy (n: 16, 22%); (3) demyelinating motor and sensory polyneuropathy (n: 13, 17%); (4) pure sensory polyneuropathy (n: 11, 15%); (5) high-low syndrome (n: 2, 3%). Etiologic factors were identified in all of the patients with three electrodiagnostic patterns of polyneuropathy: acute axonal, pure sensory, and high-low syndrome. However, etiologic factors could not be determined in 5 (31%) children with chronic axonal polyneuropathy and in 3 (23%) children with demyelinating sensory and motor polyneuropathy. Among children with the acute axonal pattern, toxic causes were evident in 18 (56%), acute motor axonal neuropathy in 11 (35%), and acute motor sensory axonal polyneuropathy in 3 (9%). Nine (82%) patients with pure sensory polyneuropathy had diabetes mellitus. In conclusion, a thorough history and physical examination in conjunction with specific electrodiagnostic patterns might provide a cost-effective and rational differential diagnosis of childhood polyneuropathies. (c) 2006 by Elsevier Inc. All rights reserved.en_US
dc.identifier.doi10.1016/j.pediatrneurol.2005.11.002en_US
dc.identifier.endpage17en_US
dc.identifier.issn0887-8994
dc.identifier.issue1en_US
dc.identifier.pmid16814079en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage11en_US
dc.identifier.urihttps://doi.org/10.1016/j.pediatrneurol.2005.11.002
dc.identifier.urihttps://hdl.handle.net/11454/38536
dc.identifier.volume35en_US
dc.identifier.wosWOS:000239190400003en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElsevier Science Incen_US
dc.relation.ispartofPediatric Neurologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.titleElectrodiagnostic pattern approach for childhood polyneuropathiesen_US
dc.typeArticleen_US

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