Herpes simplex encephalitis: diffusion MR imaging findings

dc.contributor.authorSener, RN
dc.date.accessioned2019-10-27T18:19:25Z
dc.date.available2019-10-27T18:19:25Z
dc.date.issued2001
dc.departmentEge Üniversitesien_US
dc.description.abstractWe studied five patients with herpes simplex encephalitis type I with diffusion-weighted MR imaging, as this sequence provides information regarding tissue integrity. Diffusion-weighted imaging was obtained using the echo-planar sequence. True diffusion images (i.e. b = 1000 s/mm(2) images), and the ADC (apparent diffusion coefficient) values were studied. In addition, diffusion imaging of 12 normal cases, 46 patients with acute ischemia (cytotoxic edema), and 12 patients with vasogenic edema were studied for comparison. La patients with herpes encephalitis, two distinct types of diffusion imaging findings (on b = 1000 s/mm(2) images, and ADC maps) were noted: lesions similar to cytotoxic edema, and lesions similar to vasogenic edema. The patients with the former type of lesions had fulminating disease, and were in severe clinical condition. Those with the latter represented early cases, and they were in fairly good clinical condition with a good outcome by prompt therapy. Diffusion imaging appears to be a promising sequence to monitor the changes in the brain tissue in herpes encephalitis, and in other infections as well with respect to restriction of movement (cytotoxic edema) or relatively high-motion (vasogenic edema) of water molecules, providing data on the severity of the disease. (C) 2001 Elsevier Science Ltd. All rights reserved.en_US
dc.identifier.doi10.1016/S0895-6111(01)00005-2en_US
dc.identifier.endpage397en_US
dc.identifier.issn0895-6111
dc.identifier.issue5en_US
dc.identifier.pmid11390193en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage391en_US
dc.identifier.urihttps://doi.org/10.1016/S0895-6111(01)00005-2
dc.identifier.urihttps://hdl.handle.net/11454/35663
dc.identifier.volume25en_US
dc.identifier.wosWOS:000170518600004en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherPergamon-Elsevier Science Ltden_US
dc.relation.ispartofComputerized Medical Imaging and Graphicsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectbrainen_US
dc.subjectinflammationen_US
dc.subjectencephalitisen_US
dc.subjectherpesvirus type 1en_US
dc.subjectdiffusion-weighted MR imagingen_US
dc.titleHerpes simplex encephalitis: diffusion MR imaging findingsen_US
dc.typeArticleen_US

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