Ovarian cysts in postmenopausal tamoxifen-treated breast cancer patients with endometrial thickening detected by transvaginal sonography

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dc.contributor.authorKazandi, M
dc.contributor.authorSendag, F
dc.contributor.authorAkercan, F
dc.contributor.authorTerek, MC
dc.contributor.authorOzsaran, A
dc.contributor.authorDikmen, Y
dc.date.accessioned2019-10-27T18:18:31Z
dc.date.available2019-10-27T18:18:31Z
dc.date.issued2002
dc.departmentEge Üniversitesien_US
dc.description.abstractObjective: To investigate the frequency of ovarian cysts in tamoxifen-treated postmenopausal breast cancer patients with endometrial thickening detected by transvaginal sonography. Methods: Medical records and transvaginal sonographies of 38 postmenopausal women treated for breast cancer with adjuvant tamoxifen therapy who had undergone endometrial sampling due to abnormal endometrial thickness were reviewed retrospectively. Results: During the study period five of 38 tamoxifen-treated postmenopausal patients (13.2%) had ovarian cysts. The mean tamoxifen treatment interval of the patients with an ovarian cyst was 22.4 +/- 18.4 months (p = 0.17). The mean endometrial thickness of the patients with an ovarian cyst was 12.6 +/- 5.9 mm (p = 0.17). Endometrial biopsy detected six cases of abnormal endometria, including endometrial carcinoma (n = 1), endometrial polyp (n = 1) and simple endometrial hyperplasia without atypia (n = 4). Three patients with ovarian cysts underwent laparatomy revealing simple cysts on histopathological examination. Two patients with ovarian cysts declined laparatomy and are currently under follow-up. Conclusion: Ovarian cysts a common side-effect of tamoxifen treatment in postmenopausal tamoxifen-treated breast cancer patients. Transvaginal sonography should be performed to detect any concomitant endometrial pathology.en_US
dc.identifier.endpage260en_US
dc.identifier.issn0392-2936
dc.identifier.issue3en_US
dc.identifier.pmid12094966en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage257en_US
dc.identifier.urihttps://hdl.handle.net/11454/35499
dc.identifier.volume23en_US
dc.identifier.wosWOS:000176196700021en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherI R O G Canada, Incen_US
dc.relation.ispartofEuropean Journal of Gynaecological Oncologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjecttamoxifenen_US
dc.subjectendometriumen_US
dc.subjectpostmenopauseen_US
dc.subjectovarian cysten_US
dc.titleOvarian cysts in postmenopausal tamoxifen-treated breast cancer patients with endometrial thickening detected by transvaginal sonographyen_US
dc.typeArticleen_US

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