The Follow-Up of Biomarkers Better Predicts the Poor Outcome in COVID-19 Patients

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dc.contributor.authorBasoglu, Ozen K.
dc.contributor.authorOzhan, Mustafa Hikmet
dc.contributor.authorEkren, Pervin Korkmaz
dc.contributor.authorAk, Gunes
dc.contributor.authorTasbakan, Mehmet Sezai
dc.contributor.authorSayiner, Abdullah
dc.date.accessioned2021-05-03T20:36:56Z
dc.date.available2021-05-03T20:36:56Z
dc.date.issued2020
dc.departmentEge Üniversitesien_US
dc.description.abstractObjective. To investigate the course of biomarkers on admission and follow-up in order to identify early predictors for poor outcome in COVID-19 patients. Methods. in this study, 132 COVID-19 patients were classified as good outcome (n=62) and poor outcome (n=70) groups. Laboratory parameters were evaluated on admission and within 5-7 days after hospitalization. Results. Baseline levels of neutrophil-lymphocyte ratio, CRP, procalcitonin, ferritin, D-dimer and LDH were higher (p<0.01); lymphocyte count was lower in the poor outcome patients. During follow-up there was a larger decrease in lymphocyte count and more prominent increases in other biomarkers (p<0.001). in ROC analysis, the AUCs strongly indicated the poor outcome on days 5-7 of the hospitalization. Conclusions. This study suggests that the follow-up measurements of the biomarkers better predict the poor outcome in COVID-19 pneumonia.en_US
dc.identifier.endpage851en_US
dc.identifier.issn0091-7370
dc.identifier.issn1550-8080
dc.identifier.issue6en_US
dc.identifier.pmid33334804en_US
dc.identifier.startpage848en_US
dc.identifier.urihttps://hdl.handle.net/11454/70276
dc.identifier.volume50en_US
dc.identifier.wosWOS:000599944900021en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherAssoc Clinical Scientistsen_US
dc.relation.ispartofAnnals of Clinical and Laboratory Scienceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCOVID-19en_US
dc.subjectbiomarkersen_US
dc.subjectviral pneumoniaen_US
dc.subjectprognosisen_US
dc.subjectclinical outcomeen_US
dc.titleThe Follow-Up of Biomarkers Better Predicts the Poor Outcome in COVID-19 Patientsen_US
dc.typeArticleen_US

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