Characteristics and Treatment Results of 5 Patients with Fibrous Dysplasia and Review of the Literature

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dc.contributor.authorKutbay, Nilufer Ozdemir
dc.contributor.authorYurekli, Banu Sarer
dc.contributor.authorBaykan, Emine Kartal
dc.contributor.authorSahin, Serap Baydur
dc.contributor.authorSaygili, Fusun
dc.date.accessioned2019-10-27T22:28:59Z
dc.date.available2019-10-27T22:28:59Z
dc.date.issued2015
dc.departmentEge Üniversitesien_US
dc.description.abstractAim. Fibrous dysplasia is a rare bone disease caused by missense mutation leading to abnormal fibroblast and osteoblast proliferation and increased bone resorption. FD can present in monostotic or polyostotic forms. About 3% of FD could be in association with McCune-Albright syndrome (MAS). Because FD is a rare disease, there is limited data in the literature about characteristics of disease and response to treatment. Methods. We present our five cases of FD with general properties and their responses to medical treatment. Results. Two of our patients had polyostotic and three had monostotic FD. One of the polyostotic patients had MAS. One of our patients had surgery for femur fractures, facial asymmetry, and findings of compression. Four patients were given pamidronate; one was given zoledronic acid as bisphosphonate treatment. Bone pain was relieved in all patients with medical treatment. Conclusion. There was a decrease in bone turnover markers to some degree with medical treatment but no radiological improvement was observed.en_US
dc.identifier.doi10.1155/2015/670809en_US
dc.identifier.issn2090-6501
dc.identifier.issn2090-651X
dc.identifier.pmid26171261en_US
dc.identifier.urihttps://doi.org/10.1155/2015/670809
dc.identifier.urihttps://hdl.handle.net/11454/51020
dc.identifier.wosWOS:000369664000001en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherHindawi Publishing Corpen_US
dc.relation.ispartofCase Reports in Endocrinologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleCharacteristics and Treatment Results of 5 Patients with Fibrous Dysplasia and Review of the Literatureen_US
dc.typeArticleen_US

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