Changing epidemiology of hepatitis A infection in Izmir, Turkey

Basit Öğe Kaydı
dc.contributor.authorKurugol, Zafer
dc.contributor.authorAslan, Asli
dc.contributor.authorTurkoglu, Ebru
dc.contributor.authorKoturoglu, Guldane
dc.date.accessioned2019-10-27T21:36:59Z
dc.date.available2019-10-27T21:36:59Z
dc.date.issued2011
dc.departmentEge Üniversitesien_US
dc.description.abstractThe seroprevalence study was conducted in order to determine the current seroepidemiology hepatitis A in Izmir, Turkey and to evaluate the epidemiological shift in HAV serostatus. Blood samples collected from 595 subjects aged 1-60 years were analyzed for anti-HAV IgG antibodies. The current study results were compared with those of a previous study conducted in 1998 involving the same location. There was a marked decrease in the prevalence of anti-HAV between 1998 and 2008. While anti-HAV seroprevalence rates in the current study were 4.6% in children aged 1-4 years, 23% in children aged 10-14 years, and 85% in young adults aged 20-29 years, the prevalence rates were 36% in the 1-4 years age group, 65% in the 10-14 years age group, and 95% in young adults in the previous study, indicating a shift in HAV seroprevalence from the younger to the higher age groups. As HAV infection in childhood is decreasing, the pool of susceptible adolescents and young adults is increasing in Izmir, Turkey. The majority of adolescent population is susceptible to HAV infection. The potential risk of HAV epidemics still exists. The situation of Turkey, suggested to need for mass immunization. Also, introduction of hepatitis A vaccination into the national immunization schedule of Turkey should be considered. (C) 2011 Elsevier Ltd. All rights reserved.en_US
dc.identifier.doi10.1016/j.vaccine.2011.06.069en_US
dc.identifier.endpage6261en_US
dc.identifier.issn0264-410X
dc.identifier.issue37en_US
dc.identifier.pmid21763745en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage6259en_US
dc.identifier.urihttps://doi.org/10.1016/j.vaccine.2011.06.069
dc.identifier.urihttps://hdl.handle.net/11454/46149
dc.identifier.volume29en_US
dc.identifier.wosWOS:000295243800014en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElsevier Sci Ltden_US
dc.relation.ispartofVaccineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectHepatitis Aen_US
dc.subjectPrevalenceen_US
dc.subjectVaccinationen_US
dc.titleChanging epidemiology of hepatitis A infection in Izmir, Turkeyen_US
dc.typeArticleen_US

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