Inflammatory marker levels in obese adolescents with glucose intolerance: Increased chitotriosidase activity

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dc.contributor.authorKabaroglu, Ceyda
dc.contributor.authorOnur, Ece
dc.contributor.authorBarutcuoglu, Burcu
dc.contributor.authorOzhan, Bayram
dc.contributor.authorErdinc, Soner
dc.contributor.authorVar, Ahmet
dc.contributor.authorBayindir, Oya
dc.contributor.authorErsoy, Betul
dc.date.accessioned2019-10-27T21:43:57Z
dc.date.available2019-10-27T21:43:57Z
dc.date.issued2012
dc.departmentEge Üniversitesien_US
dc.description.abstractObjectives: Existance of low grade persistent inflammation in obese children may increase the risk of metabolic and cardiovascular events. The aim was to determine whether glucose intolerance has an influence on inflammatory markers in obese adolescents. Designs and methods: 45 obese adolescents (mean BMI: 30.34 +/- 5.42 kg/m(2)) were grouped as normal or impaired glucose tolerance. IL-6 and CRP levels were analyzed by commercially available kits. Chitotriosidase activity was measured by a fluorescence method and neopterin levels were determined by ELISA. Data were expressed as mean +/- SD. Results: IL-6 and CRP levels were similar in the two groups. Serum neopterin levels were not different between the groups. The chitotriosidase activity was significantly higher in the IGT group than NGT (124.33 +/- 51.97 mu mol/L/h vs 84.50 +/- 53.99 mu mol/L/h, p = 0.04). Conclusion: Serum chitotriosidase activity is increased in obese adolescents with impaired glucose tolerance. (C) 2011 The Canadian Society of Clinical Chemists. Published by Elsevier Inc. All rights reserved.en_US
dc.identifier.doi10.1016/j.clinbiochem.2011.12.007en_US
dc.identifier.endpage284en_US
dc.identifier.issn0009-9120
dc.identifier.issn1873-2933
dc.identifier.issue04.Mayen_US
dc.identifier.pmid22206738en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage281en_US
dc.identifier.urihttps://doi.org/10.1016/j.clinbiochem.2011.12.007
dc.identifier.urihttps://hdl.handle.net/11454/47173
dc.identifier.volume45en_US
dc.identifier.wosWOS:000302844500002en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherPergamon-Elsevier Science Ltden_US
dc.relation.ispartofClinical Biochemistryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectChitotriosidaseen_US
dc.subjectObesityen_US
dc.subjectInflammationen_US
dc.titleInflammatory marker levels in obese adolescents with glucose intolerance: Increased chitotriosidase activityen_US
dc.typeArticleen_US

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