Analysis of Prognostic Factors Affecting Cancer-specific Survival in Renal Tumors Larger than Ten Centimeters

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dc.contributor.authorKızılay, Fuat
dc.contributor.authorŞimşir, Adnan
dc.contributor.authorAkıncıoğlu, Emir
dc.contributor.authorKalemci, Serdar
dc.contributor.authorÇal, Çağla
dc.contributor.authorCüreklibatır, İbrahim
dc.contributor.authorKumbaracı, Banu Sarsık
dc.date.accessioned2021-05-03T21:13:50Z
dc.date.available2021-05-03T21:13:50Z
dc.date.issued2019
dc.departmentEge Üniversitesien_US
dc.description.abstractObjective: The aim of this study was to evaluate the relationship between prognostic factors and cancer-specific survival (CSS) in renal tumors larger than ten centimeters. Materials and Methods: We evaluated the data of 126 patients who underwent open radical nephrectomy due to a renal mass larger than 10 cm between January 2010 and June 2016. Kaplan-Meier analysis or Cox regression was used to analyze the relationship between CSS and variables. Pairwise group comparisons were also evaluated with the Log-Rank test. A p-value <0.05 was considered statistically significant. Results: Mean follow-up was 68.5 months and mean survival was 39.2 months. The relationships between tumor histopathology, stage and CSS were significant. Tumor size negatively affected CSS, but the relationship was not significant. Tumor stage (T2b, T3b), tumor thrombus, lymph node metastasis and adjuvant therapy were the most effective independent factors affecting CSS according to Cox regression analysis results. Conclusion: Although tumor size is an important prognostic factor for T2b and lower stage kidney tumors, this effect is less in larger tumors and other clinicopathological features should be considered further to predict prognosis.en_US
dc.identifier.doi10.4274/uob.galenos.2019.1184
dc.identifier.endpage106en_US
dc.identifier.issn2147-2122
dc.identifier.issn2147-2270
dc.identifier.issue3en_US
dc.identifier.startpage99en_US
dc.identifier.urihttps://doi.org/10.4274/uob.galenos.2019.1184
dc.identifier.urihttps://app.trdizin.gov.tr/makale/TXpjNU1Ua3hNUT09
dc.identifier.urihttps://hdl.handle.net/11454/71668
dc.identifier.volume18en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.ispartofÜroonkoloji Bültenien_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subject[No Keywords]en_US
dc.titleAnalysis of Prognostic Factors Affecting Cancer-specific Survival in Renal Tumors Larger than Ten Centimetersen_US
dc.typeArticleen_US

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