Do tumor size and location affect survival in upper urinary tract urothelial carcinoma?

Basit Öğe Kaydı
dc.contributor.authorKalemci, Serdar
dc.contributor.authorErgün, Kasım Emre
dc.contributor.authorKızılay, Fuat
dc.contributor.authorŞimşir, Adnan
dc.contributor.authorKöse, Timur
dc.date.accessioned2024-08-25T18:38:16Z
dc.date.available2024-08-25T18:38:16Z
dc.date.issued2023
dc.departmentEge Üniversitesien_US
dc.description.abstractAim: This study aimed to evaluate the effect of tumor location based on clinicopathologic features on cancer-specific survival (CSS) of patients who were treated surgically for locally/locally advanced upper tract urothelial carcinoma (UTUC). Materials and Methods: A single-center series of 145 patients with UTUC who underwent radical nephroureterectomy between May 2010 and August 2019 were included in the study. Patients were stratified based on the location of the tumor as renal pelvis and ureter located tumor. Clinicopathologic characteristics and oncological outcomes were compared according to tumor location and CSS rates after surgery were graphically explored using Kaplan–Meier curves. Results: At a mean follow-up time of 41.8 (4-124) months after surgery, 65 patients (44.8%) died from UTUC. Kaplan-Meier curves showed that tumor location was not associated with CSS in the analysis performed according to tumor stage, grade, and size. In the analysis that was conducted without regard to tumor location, worse CSS was found for patients with pT3 disease versus those with ?pT2 and with high-grade tumors versus those with low-grade (p=0.025 and p=0.011, respectively). Conclusion: Tumor location was not associated with CSS in any of the analyses. Regardless of tumor location, patients with pT3 disease and high-grade tumors, have a worse prognosis. Further studies on prognostic factors are needed to evaluate the advantages of these factors in the management of patients with UTUC.en_US
dc.identifier.endpage338en_US
dc.identifier.issn1016-9113
dc.identifier.issn2147-6500
dc.identifier.issue3en_US
dc.identifier.startpage332en_US
dc.identifier.trdizinid1196593en_US
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1196593
dc.identifier.urihttps://hdl.handle.net/11454/100933
dc.identifier.volume62en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.ispartofEge Tıp Dergisien_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmz20240825_Gen_US
dc.titleDo tumor size and location affect survival in upper urinary tract urothelial carcinoma?en_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

TR-Dizin İndeksli Yayınlar Koleksiyonu