Pulmoner Arter Basınçları 21–24 mmHg Aralığında Olan Hastaların Uzun Vadeli Doğal Seyri: Tek Merkez Deneyimi

dc.authorscopusid57191909085
dc.authorscopusid57202353075
dc.authorscopusid23568467100
dc.authorscopusid7004155093
dc.authorscopusid6701848586
dc.contributor.authorYağmur, B.
dc.contributor.authorKayıkçıoğlu, M.
dc.contributor.authorŞimşek, E.
dc.contributor.authorNalbantgil, S.
dc.contributor.authorKültürsay, H.
dc.date.accessioned2024-08-25T18:45:33Z
dc.date.available2024-08-25T18:45:33Z
dc.date.issued2023
dc.departmentEge Üniversitesien_US
dc.description.abstractOBJECTIVE: Slightly elevated mean pulmonary artery pressure (mPAP) was previously termed as ''borderline pulmonary hypertension (PH)''. We examined the long-term prognosis of patients with mPAP values between 21 and 24 mmHg, who were referred with the suspicion of pulmonary hypertension. METHODS: Our retrospective study included patients with moderate-to-high echocardiographic risk who underwent right heart catheterization (RHC) between 2008 and 2021 and were followed for at least 1 year. Patients with mPAP <21 mmHg and mPAP 21-24 mmHg were compared. Demographic and clinical characteristics and prognoses of the groups were compared. All-cause mortality over a mean follow-up of 5 years (min 1-max 13 years) was evaluated. RESULTS: A total of 140 patients (mean age 53.1 ± 14.8 years, female 74.5%) with mPAP values <25 mmHg measured of the 395 diagnostic RHCs. Mean follow-up was 4.92 ± 3.13 years. NT-pro-BNP and 6-min walking distance were better in patients with mPAP <21 mmHg. Echocardiographic findings suggestive of PH were more common in mPAP 21-24 mmHg group (P < 0.05). Both the pulmonary artery wedge pressure and cardiac index values were significantly deteriorated in individuals with mPAP 21-24 mmHg (P = 0.001). All-cause mortality tended to be higher in the borderline PH group but did not reach to statistical significance. CONCLUSION: Our single-center observational study revealed that the individuals with an mPAP of 21-24 mmHg tended to have a worser prognosis than those with mPAP of <21 mmHg for up to 13-year follow-up.en_US
dc.identifier.doi10.5543/tkda.2023.65724
dc.identifier.endpage485en_US
dc.identifier.issn1308-4488
dc.identifier.issue7en_US
dc.identifier.pmid37861260en_US
dc.identifier.scopus2-s2.0-85174865097en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage478en_US
dc.identifier.urihttps://doi.org/10.5543/tkda.2023.65724
dc.identifier.urihttps://hdl.handle.net/11454/101607
dc.identifier.volume51en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.relation.ispartofTurk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidiren_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmz20240825_Gen_US
dc.subjectadulten_US
dc.subjectageden_US
dc.subjectfemaleen_US
dc.subjectheart catheterizationen_US
dc.subjecthemodynamicsen_US
dc.subjecthumanen_US
dc.subjectlung wedge pressureen_US
dc.subjectmiddle ageden_US
dc.subjectpulmonary arteryen_US
dc.subjectpulmonary hypertensionen_US
dc.subjectretrospective studyen_US
dc.subjectAdulten_US
dc.subjectAgeden_US
dc.subjectCardiac Catheterizationen_US
dc.subjectFemaleen_US
dc.subjectHemodynamicsen_US
dc.subjectHumansen_US
dc.subjectHypertension, Pulmonaryen_US
dc.subjectMiddle Ageden_US
dc.subjectPulmonary Arteryen_US
dc.subjectPulmonary Wedge Pressureen_US
dc.subjectRetrospective Studiesen_US
dc.titlePulmoner Arter Basınçları 21–24 mmHg Aralığında Olan Hastaların Uzun Vadeli Doğal Seyri: Tek Merkez Deneyimien_US
dc.title.alternativeLong-Term Natural Course of Patients with Pulmonary Artery Pressures in the Range of 21-24 mmHg: Insights from a Single-Center Studyen_US
dc.typeArticleen_US

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