The efficacy of paracetamol versus tenoxicam on postoperative pain and morphine consumption after abdominal hysterectomy: a placebo-controlled, randomized study

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dc.contributor.authorGunusen, I.
dc.contributor.authorKaraman, S.
dc.contributor.authorAcar, A.
dc.contributor.authorSargin, A.
dc.contributor.authorFirat, V.
dc.date.accessioned2019-10-27T21:34:14Z
dc.date.available2019-10-27T21:34:14Z
dc.date.issued2012
dc.departmentEge Üniversitesien_US
dc.description.abstractObjective: The purpose of this study was to determine the analgesic efficacy and side-effects of paracetamol and tenoxicam in comparison with placebo in patients with postoperative pain after elective abdominal hysterectomy. Material and Methods: A total of 120 patients were randomly divided into three groups to receive either paracetamol 1 g, tenoxicam 20 mg or placebo intravenously at the end of surgery, and then morphine was administered by a patient-controlled analgesia device postoperatively. Results: Tenoxicam was associated with lower pain scores at the 2nd, 4th, 6th and 24th hour postoperatively. Total morphine consumption was 44.8 +/- 17.4 mg, 64.6 +/- 19.6 mg, 69.2 +/- 22.1 (tenoxicam, paracetamol and placebo group, respectively) and there was a significant difference in the tenoxicam group compared with the other two groups (p < 0.05). Side-effects except for nausea were similar. Conclusion: A single dose of 20 mg tenoxicam provided effective analgesia and reduced total morphine consumption in comparison with paracetamol and placebo after abdominal hysterectomy.en_US
dc.identifier.endpage52en_US
dc.identifier.issn0390-6663
dc.identifier.issue1en_US
dc.identifier.pmid22675955en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage49en_US
dc.identifier.urihttps://hdl.handle.net/11454/45607
dc.identifier.volume39en_US
dc.identifier.wosWOS:000301509900012en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherI R O G Canada, Incen_US
dc.relation.ispartofClinical and Experimental Obstetrics & Gynecologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectParacetamolen_US
dc.subjectTenoxicamen_US
dc.subjectMorphineen_US
dc.subjectPostoperative painen_US
dc.subjectAbdominal hysterectomyen_US
dc.titleThe efficacy of paracetamol versus tenoxicam on postoperative pain and morphine consumption after abdominal hysterectomy: a placebo-controlled, randomized studyen_US
dc.typeArticleen_US

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