Cephalaria transsylvanica L. 'nin minör terpenik glikozidlerinin yapılarının aydınlatılması

ABSTRAKT Cephalaria Transsylvanica L.'nin kurutulmuş çiçeklerinden; bir serbest nor-triterpen (I) ve üç nötral bisdezmozidik triterpen glikozid (II.III.IV) izole edildi. Spektroskopik, kimyasal ve kromatografik analizler sonucu; Nor-triterpenin(T) yapısı; 3pV23-dihidroksi-(17)-18-en-28-nor-oleanan, Cephalaria glikozid A (II) nın yapısı; 3-0-{[a-L-arabinopiranozil(l - >2)-a-L-arabinopiranozil]-[28-0-p-D-glukopi- ranozil] }-3|3-hidroksi-12(13)-oleanen-28-oik asit, Cephalaria glikozid B (III) nin yapısı; 3-0- { [j3-D-ksilopiranozil(l - >4)-a-L-rarnnopiranozil(l - ^>2)-P-D-ksilopirano- zil]-[28-0-P-D-glukopiranozil]}-3P,23-dihidroksi-12(13)-oleanen-28-oikasit, Cephalaria glikozid C (TV) nin yapısı; 3-0-{[pVD-glukopiranozil(l - >4)-a-L-rarnnopiranozil(l - >4)-P-D-ksilopira- nozil]-[28-0-P-D-glukopiranozil] }-3p,23-dihidroksi-12(13)-oleanen-28-oik asit ola rak belirlendi. u

ABSTRACT One free nor-triterpene(I) and three neutral bisdezmozidic triterpene glycosides (II, III, IV) were isolated from dried flowers of Cephalaria Transsylvanica. After spectroscopic, chemical and chromatographic analysis; their structures were identified as below: The structure of nor- triterpene (I) was found to be; 3p-23-dihydroxy-17(18)-en-28-nor-oleanan, The structure of Cephalaria Glycoside A (II) was found to be; 3-0-{[a-L-arabinopyranosyl(l - >2)-a-L-arabinopyranosylH28-0-{3-D-gluco- pyranosyl] }-3f5-hydroksi-12(13)-oleanene-28-oic acid, The structure of Cephalaria Glycoside B (III) was found to be; 3-0-{[P-D-xylopyranosyl(l - >4)a-L-rhamnopyranosyl(l - >2)-P-D-xylopyra- nosyl]-[28-0-P-D-glucopyranosyl]}-3P,23-dihydroxy-12(13)-oleanene-28-oicacid, Finally, the structure of Cephalaria Glycoside C (TV) was found to be; 3-0-{[|3-D-glucopyranosyl(l - >4)-a-L-rhamnopyranosyl(l - ^>4)-P-D-xylopy- ranosyl]-[28-0-p,-D-glucopyranosyl]}-3p,23-dihydroxy-12(13)-oleanene-28-oic acid. m