Cytotoxic effects of primary tooth root canal filling materials on L929 cell line

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dc.contributor.authorSarigol C.G.
dc.contributor.authorCogulu D.
dc.contributor.authorOncag O.
dc.contributor.authorDeliloglu I.G.
dc.date.accessioned2019-10-26T22:36:56Z
dc.date.available2019-10-26T22:36:56Z
dc.date.issued2010
dc.departmentEge Üniversitesien_US
dc.description.abstractPurpose: The purpose of this study was to determine the cytotoxic effects of five different, primary tooth root canal filling materials on L929 permanent cell line with MTT assay. Methods: Kri 1 paste (iodoform), Diapex (iodoform+Ca(OH)2), Metapaste (Ca(OH)2 with distilled water), Dentalis (iodoform+ZOE+Ca(OH)2) and Kalsin (Ca(OH) 2 with glycerin) were used in this study. Tested materials were in contact for 24, 48 and 72 hours with L929 cells. At the end of the test periods, MTT test solutions were added to the plates and incubated for 3 hours at 37°C. Then optic densities were read using UV visible spectrophotometer. All assays were repeated three times to ensure reproducibility. The obtained data were analyzed statistically by one-way analysis of variance and Dunnett T3 post hoc test (P<0.05). Results: All tested materials were found cytotoxic on L929 cell line. It was found that Kri 1 paste group showed the highest survival rates. Conclusions: We concluded that the use of Kri 1 paste as a root canal filling material is a better option than other medications in primary teeth. Further research is necessary to determine the effect of root canal filling materials on vital tissues.en_US
dc.identifier.endpage76en_US
dc.identifier.issn1551-8949
dc.identifier.issue2en_US
dc.identifier.pmid20819401en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage72en_US
dc.identifier.urihttps://hdl.handle.net/11454/19889
dc.identifier.volume77en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.relation.ispartofJournal of Dentistry for Childrenen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCalcium hydroxideen_US
dc.subjectCytotoxicityen_US
dc.subjectIodoformen_US
dc.subjectL929en_US
dc.subjectZinc oxide eugenolen_US
dc.titleCytotoxic effects of primary tooth root canal filling materials on L929 cell lineen_US
dc.typeArticleen_US

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