Consequences of epididymal ligation on prepubertal rats

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dc.contributor.authorAktug, Huseyin
dc.contributor.authorOzdedeli, Kaan
dc.contributor.authorAltay, Baris
dc.contributor.authorCureklibatur, Ibrahim
dc.contributor.authorTurna, Burak
dc.contributor.authorYilmaz, Ozlem
dc.date.accessioned2019-10-27T19:36:21Z
dc.date.available2019-10-27T19:36:21Z
dc.date.issued2007
dc.departmentEge Üniversitesien_US
dc.description100th Annual Meeting of the American-Urological-Association -- MAY 21-26, 2005 -- San Antonio, TXen_US
dc.description.abstractOBJECTIVE: To study prospectively experimental effects of unilateral epididymal obstruction on testis and epididymis histopathologically in prepubertal rats. STUDY DESIGN: Organ weights, mean seminiferous tubule diameter (MSTD), mean ductus epididymis diameter (MDED), mean tubular biopsy scores (MTBS) and histopathology of 21 male albino Wistar rats were compared with the immunostaining affinity of antidesmin, anti-vimentin, anti-laminin and anti-collagen antibodies. RESULTS: Statistical analysis of mean weight of testes, MTBS, mean epididymal weight, MDED and MSTD was significant. Evaluation of testis and epididymis revealed cellular damage, basal membrane impairment and granulomatous infiltration. CONCLUSION: Histopathologic alterations with MSTD are early indicators for ipsilateral and contralateral injury. Even the presence of criteria such as intactness and cellular integrity does not guarantee there is no sperm leakage or immunologic damage. Therefore the impairment of basal integrity is a switch code in determining spermatogenic failure.en_US
dc.description.sponsorshipAmer Urol Assocen_US
dc.identifier.endpage56en_US
dc.identifier.issn0884-6812
dc.identifier.issue1en_US
dc.identifier.pmid17375874en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage50en_US
dc.identifier.urihttps://hdl.handle.net/11454/39845
dc.identifier.volume29en_US
dc.identifier.wosWOS:000244500400005en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSci Printers & Publ Incen_US
dc.relation.ispartofAnalytical and Quantitative Cytology and Histologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectepididymisen_US
dc.subjectductal ectasyen_US
dc.subjectimmunohistochemistryen_US
dc.subjectligationen_US
dc.subjecttestisen_US
dc.titleConsequences of epididymal ligation on prepubertal ratsen_US
dc.typeArticleen_US

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