Effects of cardiopulmonary rehabilitation on pulmonary arterial hypertension: A prospective, randomized study

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dc.contributor.authorKarapolat, Hale
dc.contributor.authorCinar, Muyesser Ece
dc.contributor.authorTanigor, Goksel
dc.contributor.authorNalbantgil, Sanem
dc.contributor.authorKayikcioglu, Meral
dc.contributor.authorMogulkoc, Nesrin
dc.contributor.authorKultursay, Hakan
dc.date.accessioned2020-12-01T12:10:02Z
dc.date.available2020-12-01T12:10:02Z
dc.date.issued2019
dc.departmentEge Üniversitesien_US
dc.descriptionTanigor, Goksel/0000-0001-6456-7012;en_US
dc.description.abstractObjectives: This study aims to investigate the effects of cardiopulmonary rehabilitation (CPR) on cardiopulmonary function, quality of life, depression, and hemodynamic parameters in patients with pulmonary arterial hypertension (PAH) and to compare the efficacy of hospital- and home-based exercise programs. Patients and methods: Between December 2014 to May 2016, a total of 30 patients with PAH were included in the study. the patients were randomly assigned to either a hospital-based (n=15) or home-based exercise program (n=15). the hospital group was assigned to a cardiac rehabilitation (three days/week, 1 hour/week 50 to 70% maximal oxygen uptake [PvO(2)]) program for eight weeks. the home-based exercise group received home exercises alone. Before and after eight weeks of rehabilitation, all patients were evaluated for their functional status (PvO(2)), pulmonary function including forced expiratory volume in one sec (FEV1), mL, forced vital capacity (FVC), mL and FEV1/FVC%, quality of life using Short Form-36 (SF-36), depression severity using Beck Depression Inventory, and hemodynamic parameters including left ventricular ejection fraction, right ventricular ejection fraction, left ventricular end-systolic diameter, left ventricular end-diastolic diameter, and systolic pulmonary arterial pressure. Results: of the patients, 12 completed the study in each group. There was no statistically significant difference in the functional status, quality of life, depression severity, and hemodynamic parameters after the rehabilitation compared baseline between the groups. Conclusion: Based on our study results, short-term CPR seems not to be beneficial in patients with PAH. We recommend long-term rehabilitation programs to achieve more benefits from aerobic exercise training in this patient population.en_US
dc.identifier.doi10.5606/tftrd.2019.2758en_US
dc.identifier.endpage286en_US
dc.identifier.issn2587-0823
dc.identifier.issue3en_US
dc.identifier.pmid31663077en_US
dc.identifier.startpage278en_US
dc.identifier.urihttps://doi.org/10.5606/tftrd.2019.2758
dc.identifier.urihttps://hdl.handle.net/11454/63637
dc.identifier.volume65en_US
dc.identifier.wosWOS:000499639000010en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherBaycinar Medical Publ-Baycinar Tibbi Yayinciliken_US
dc.relation.ispartofTurkish Journal of Physical Medicine and Rehabilitationen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAerobic exerciseen_US
dc.subjectcardiopulmonary rehabilitationen_US
dc.subjectechocardiographyen_US
dc.subjecthemodynamicsen_US
dc.subjectpulmonary arterial hypertensionen_US
dc.subjectpulmonary functional testsen_US
dc.subjectquality of lifeen_US
dc.titleEffects of cardiopulmonary rehabilitation on pulmonary arterial hypertension: A prospective, randomized studyen_US
dc.typeArticleen_US

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