The Role of Hematological Parameters in Children with COVID-19, MIS- C, and Other Viral Infections

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dc.authoridGüner Özenen, Gizem/0000-0002-9725-7501
dc.authoridSahbudak Bal, Zumrut/0000-0001-9189-8220
dc.authoridYazıcı Özkaya, Pınar/0000-0002-1209-2534
dc.contributor.authorArslan, Sema Yildirim
dc.contributor.authorBal, Zumrut Sahbudak
dc.contributor.authorOzenen, Gizem Guner
dc.contributor.authorBilen, Nimet Melis
dc.contributor.authorOzkaya, Pinar Yazici
dc.contributor.authorOzkinay, Ferda
dc.contributor.authorKarapinar, Bulent
dc.date.accessioned2024-08-31T07:46:40Z
dc.date.available2024-08-31T07:46:40Z
dc.date.issued2023
dc.departmentEge Üniversitesien_US
dc.description.abstractObjective: It is known that coronavirus disease-2019 (COVID-19) showed a clinical course with milder symptoms in children than in adults. However, a multisystem inflammatory syndrome in children (MIS-C), which developed 2-4 weeks after COVID-19 infection, emerged in April 2021. Other respiratory viruses such as influenza, respiratory syncytial virus, and parainfluenza spread worldwide after loosening pandemic restrictions. Pediatricians were challenged to distinguish COVID-19, MIS-C, and other viral infections from each other. Herein, we have aimed to determine basic, simple hematological parameters that can predict the prognosis and outcomes of the patients with COVID-19 and MIS-C. Method: In this study, 300 pediatric inpatients including those with MIS-C, COVID-19, and other respiratory virus infections admitted to Ege University Faculty of Medicine between January 2018 and September 2021, were retrospectively evaluated. Results: The neutrophil-to-lymphocyte ratio (NLR), neutrophil- to-monocyte ratio (NMR), derived NLR, and the systemic inflammatory index were higher in the MIS- C patients compared to others. The lymphocyte-to-monocyte ratio (LMR) and platelet- to-lymphocyte ratio ( PLR) were lower in children with COVID- 19 disease than those with MIS-C (p<0.05). Conclusions: In this study, we have shown that commonly used hematological tests, especially higher values of NLR, NMR for children with MIS- C, and lower levels of LMR for children with COVID-19, are significant and can help to determine the possible disease course of children at an early stage.en_US
dc.identifier.doi10.4274/jbuch.galenos.2023.21703
dc.identifier.endpage169en_US
dc.identifier.issn2822-4469
dc.identifier.issue3en_US
dc.identifier.startpage160en_US
dc.identifier.trdizinid1251542en_US
dc.identifier.urihttps://doi.org/10.4274/jbuch.galenos.2023.21703
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1251542
dc.identifier.urihttps://hdl.handle.net/11454/104165
dc.identifier.volume13en_US
dc.identifier.wosWOS:001189207200003en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.publisherGalenos Publ Houseen_US
dc.relation.ispartofJournal of Behcet Uz Childrens Hospitalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmz20240831_Uen_US
dc.subjectCovid-19en_US
dc.subjectLymphocyte-To-Monocyte Ratioen_US
dc.subjectMultisystem Inflammatory Syndrome In Children (Mis-C)en_US
dc.subjectNeutrophil-To-Lymphocyte Ratioen_US
dc.subjectOther Virusesen_US
dc.titleThe Role of Hematological Parameters in Children with COVID-19, MIS- C, and Other Viral Infectionsen_US
dc.typeArticleen_US

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