Drug-induced acute interstitial nephritis and vasculitis or vasculary rejection in renal allografts.

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dc.contributor.authorSen S.
dc.contributor.authorBayrak R.
dc.contributor.authorOk E.
dc.contributor.authorBaşdemir G.
dc.date.accessioned2019-10-27T00:25:23Z
dc.date.available2019-10-27T00:25:23Z
dc.date.issued2001
dc.departmentEge Üniversitesien_US
dc.description.abstractWe describe a patient who sought treatment for acute renal allograft dysfunction 2 weeks after renal transplantation. Renal allograft biopsy (RAB) showed intimal arteritis, severe interstitial infiltration with a few eosinophils, and severe tubulitis. Pathologic diagnosis was acute rejection (grade 2b- Banff 93); however, another clinical diagnosis, drug-induced acute interstitial nephritis (AIN), was not excluded. Before the RAB, his trimethaprim-sulfamethoxazole (TMP-SMZ) treatment was discontinued. Renal function began to improve on biopsy day without antirejection therapy. Recovery of renal function without antirejection treatment and discontinuation of TMP-SMZ shows that renal pathology might be related to drug-induced dysfunction and drug-induced AIN and vasculitis. After 5 years, the patient and his renal allograft function are both well.en_US
dc.description.sponsorshipNational Kidney Foundationen_US
dc.description.sponsorshipFrom the Department of Pathology, Section of Nephrology, Ege University, Medicine Faculty, Bornova, Izmir, Turkey. Received February 28, 2000; accepted in revised form September 15, 2000. Address reprint requests to Sait S¸en, MD, Ege Üniversi-tesi Tip Fakültesi, Patoloji Anabilim Dalı Bornova Izmir, 35040 Turkey. E-mail: saitsen@med.ege.edu.tr © 2001 by the National Kidney Foundation, Inc. 1523-6838/01/3701-0027$3.00/0 doi:10.1053/ajkd.2001.20626 --en_US
dc.identifier.issn1523-6838
dc.identifier.issue1en_US
dc.identifier.pmid11136193en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.urihttps://hdl.handle.net/11454/23240
dc.identifier.volume37en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.relation.ispartofAmerican journal of kidney diseases : the official journal of the National Kidney Foundationen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.titleDrug-induced acute interstitial nephritis and vasculitis or vasculary rejection in renal allografts.en_US
dc.typeArticleen_US

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