Long-term surgical outcomes in pediatric ovarian neoplasms: 20-year single-center experience

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dc.authorscopusid57280014000
dc.authorscopusid6506825310
dc.authorscopusid35236739700
dc.authorscopusid6701613383
dc.authorscopusid6603762840
dc.authorscopusid57196590497
dc.contributor.authorKurtmen, Bade Toker
dc.contributor.authorDokumcu, Zafer
dc.contributor.authorDivarci, Emre
dc.contributor.authorErgun, Orkan
dc.contributor.authorOzok, Geylani
dc.contributor.authorCelik, Ahmet
dc.date.accessioned2023-01-12T19:50:09Z
dc.date.available2023-01-12T19:50:09Z
dc.date.issued2022
dc.departmentN/A/Departmenten_US
dc.description.abstractPurpose The management of pediatric ovarian neoplasms (ON) is based on finding a balance between adequate surgical treatment and future reproductive capacity. We aimed to evaluate long-term results of patients who underwent surgery for ON. Methods A retrospective cohort study design was used. Medical records of patients with ON were reviewed. They were invited to participate in a telephone-based survey assessing complaints, menstrual status, and post-surgical recurrence. Results Eighty-five patients were operated for ON between 1995 and 2015. Median age at surgery was 14.7 years. 62.4% of patients had ovary-sparing surgery (OSS). Median tumor size in oophorectomy group was significantly larger than OSS group (p = 0.029). Median length of follow-up was 5.1 years. Recurrent/metachronous disease was not significantly different between OSS and oophorectomy groups (p = 1.000). In OSS group, irregular menses (p = 0.004) and painful menses (p = 0.002) were significantly higher than oophorectomy group. Conclusion The main goal of treatment in pediatric ON is to find the right balance between adequate and appropriate tumor resection and maximal effort for fertility preservation. Our results showed no difference between oophorectomy and OSS in the terms of recurrence. Although irregular and painful menses were found to be significantly higher in the OSS group, longer follow-up and prospective studies are needed to clarify this issue.en_US
dc.identifier.doi10.1007/s00383-022-05256-2
dc.identifier.endpage2044en_US
dc.identifier.issn0179-0358
dc.identifier.issn1437-9813
dc.identifier.issue12en_US
dc.identifier.pmid36169670en_US
dc.identifier.scopus2-s2.0-85139168907en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage2035en_US
dc.identifier.urihttps://doi.org/10.1007/s00383-022-05256-2
dc.identifier.urihttps://hdl.handle.net/11454/76032
dc.identifier.volume38en_US
dc.identifier.wosWOS:000861118000003en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofPediatric Surgery Internationalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectOvarian neoplasmen_US
dc.subjectChildrenen_US
dc.subjectOvary-sparing surgeryen_US
dc.subjectOophorectomyen_US
dc.subjectFertilityen_US
dc.subjectEarly Menopauseen_US
dc.subjectAdnexal Massesen_US
dc.subjectTumor-Markersen_US
dc.subjectManagementen_US
dc.subjectChildrenen_US
dc.subjectPreservationen_US
dc.subjectFertilityen_US
dc.subjectBorderlineen_US
dc.subjectMalignancyen_US
dc.subjectPredictorsen_US
dc.titleLong-term surgical outcomes in pediatric ovarian neoplasms: 20-year single-center experienceen_US
dc.typeArticleen_US

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