Association of Age, Sex, and Heart Failure Etiology in Continuous Flow Left Ventricular Assist Device Patients

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dc.authorscopusid40661114300
dc.authorscopusid57189350968
dc.authorscopusid57205137616
dc.authorscopusid57735837700
dc.authorscopusid6603075845
dc.authorscopusid7003267009
dc.contributor.authorBalcioglu, O.
dc.contributor.authorKahraman, Ü.
dc.contributor.authorErgi, D.G.
dc.contributor.authorKaraca, S.
dc.contributor.authorEngin, C.
dc.contributor.authorYagdi, T.
dc.date.accessioned2024-08-25T18:32:09Z
dc.date.available2024-08-25T18:32:09Z
dc.date.issued2023
dc.departmentEge Üniversitesien_US
dc.description.abstractBackground: Advanced heart failure studies demonstrate that ischemic factors increase in prevalence with age and are more prominent in men. Ejection fraction (EF) cannot be preserved in these patients, and ischemic cardiomyopathy develops. Non-ischemic factors are more prominent in female heart failure patients, where the EF is preserved. Although an age-associated increase in the rate of heart failure is acknowledged in both sexes, etiologic classifications by sex-based age groups are still lacking. This study examined the etiology of heart failure according to age and sex in ventricular assist device patients. Methods: The patient population included 457 end-stage heart failure patients who received a continuous flow–left ventricular assist device at Ege University Hospital between 2010 and 2017. Age, sex, and cardiomyopathy etiology data were obtained from the hospital database. The Mann-Whitney U test was applied to test the statistical significance among subgroups (95% CI, P <.05 for statistical significance). Results: The prevalence of ischemic cardiomyopathy was significantly lower in male patients aged 18 to 39 years compared to older patients. Conversely, no difference was seen among female patients. The prevalence of dilated cardiomyopathy was higher in male patients who were 18 to 39 years of age compared to older patients, but no difference was present among the female patients. Conclusions: Age and heart failure etiology were demonstrated to be interrelated in men but not in women. The fact that etiologic factors of advanced heart failure in women have a wider range than in men makes the current classification systems insufficient for use in female populations. © 2023 Elsevier Inc.en_US
dc.identifier.doi10.1016/j.transproceed.2023.01.031
dc.identifier.endpage1296en_US
dc.identifier.issn0041-1345
dc.identifier.issue5en_US
dc.identifier.pmid37147195en_US
dc.identifier.scopus2-s2.0-85157999058en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage1294en_US
dc.identifier.urihttps://doi.org/10.1016/j.transproceed.2023.01.031
dc.identifier.urihttps://hdl.handle.net/11454/100149
dc.identifier.volume55en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElsevier Inc.en_US
dc.relation.ispartofTransplantation Proceedingsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmz20240825_Gen_US
dc.subjectadulten_US
dc.subjectageen_US
dc.subjectArticleen_US
dc.subjectcorrelation analysisen_US
dc.subjectdisease classificationen_US
dc.subjectfemaleen_US
dc.subjectheart failureen_US
dc.subjecthumanen_US
dc.subjectischemic cardiomyopathyen_US
dc.subjectmajor clinical studyen_US
dc.subjectmaleen_US
dc.subjectprevalenceen_US
dc.subjectrank sum testen_US
dc.subjectsexen_US
dc.subjectstatistical significanceen_US
dc.subjectadolescenten_US
dc.subjectcomplicationen_US
dc.subjectdilated cardiomyopathyen_US
dc.subjectheart assist deviceen_US
dc.subjectheart failureen_US
dc.subjectheart left ventricle functionen_US
dc.subjectheart muscle ischemiaen_US
dc.subjectheart stroke volumeen_US
dc.subjectyoung adulten_US
dc.subjectAdolescenten_US
dc.subjectAdulten_US
dc.subjectCardiomyopathy, Dilateden_US
dc.subjectFemaleen_US
dc.subjectHeart Failureen_US
dc.subjectHeart-Assist Devicesen_US
dc.subjectHumansen_US
dc.subjectMaleen_US
dc.subjectMyocardial Ischemiaen_US
dc.subjectStroke Volumeen_US
dc.subjectVentricular Function, Leften_US
dc.subjectYoung Adulten_US
dc.titleAssociation of Age, Sex, and Heart Failure Etiology in Continuous Flow Left Ventricular Assist Device Patientsen_US
dc.typeArticleen_US

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